Latest & greatest articles for pain

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Top results for pain

61. Long-term safety and efficacy of closed-loop spinal cord stimulation to treat chronic back and leg pain (Evoke): a double-blind, randomised, controlled trial (Abstract)

Long-term safety and efficacy of closed-loop spinal cord stimulation to treat chronic back and leg pain (Evoke): a double-blind, randomised, controlled trial Spinal cord stimulation has been an established treatment for chronic back and leg pain for more than 50 years; however, outcomes are variable and unpredictable, and objective evidence of the mechanism of action is needed. A novel spinal cord stimulation system provides the first in vivo, real-time, continuous objective measure of spinal (...) cord activation in response to therapy via recorded evoked compound action potentials (ECAPs) in patients during daily use. These ECAPs are also used to optimise programming and deliver closed-loop spinal cord stimulation by adjusting the stimulation current to maintain activation within patients' therapeutic window. We aimed to examine pain relief and the extent of spinal cord activation with ECAP-controlled closed-loop versus fixed-output, open-loop spinal cord stimulation for the treatment

2020 EvidenceUpdates

62. Ibuprofen Plus Acetaminophen Versus Ibuprofen Alone for Acute Low Back Pain: An Emergency Department-based Randomized Study (Abstract)

Ibuprofen Plus Acetaminophen Versus Ibuprofen Alone for Acute Low Back Pain: An Emergency Department-based Randomized Study Patients with low back pain (LBP) are often treated with nonsteroidal anti-inflammatory drugs (NSAIDs). NSAIDs are modestly effective for LBP, but many patients with LBP continue to suffer despite treatment with these medications. We compared pain and functional outcomes 1 week after emergency department (ED) discharge among patients randomized to a 1-week course (...) LBP educational session prior to discharge. The primary outcome was improvement on the RMDQ between ED discharge and 1 week later. One secondary outcome was pain intensity, as measured on a 4-point descriptive scale (severe, moderate, mild, none) at 1 week.Enrollment began in October 2018. A total of 120 patients met selection criteria and were randomized. Baseline demographic characteristics were comparable between the two groups. By 1 week after the ED visit, patients randomized to ibuprofen

2020 EvidenceUpdates

63. Benefits and Harms of Long-term Opioid Dose Reduction or Discontinuation in Patients with Chronic Pain

Benefits and Harms of Long-term Opioid Dose Reduction or Discontinuation in Patients with Chronic Pain Management Briefs eBrief-no166 -- Benefits and Harms of Long-term Opioid Dose Reduction or Discontinuation in Patients with Chronic Pain Talk to the Veterans Crisis Line now An official website of the United States government Here's how you know The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're (...) eBrief-no166 -- Benefits and Harms of Long-term Opioid Dose Reduction or Discontinuation in Patients with Chronic Pain Health Services Research & Development Management eBrief no. 166 » Issue 166 January 2020 The report is a product of the VA/HSR&D Evidence Synthesis Program. Benefits and Harms of Long-term Opioid Dose Reduction or Discontinuation in Patients with Chronic Pain In response to the evolving public health crisis related to opioid use, many providers, health systems, and payers

2020 Veterans Affairs - R&D

64. Diagnosis and Treatment of Low Back Pain

Diagnosis and Treatment of Low Back Pain Evidence-Based Clinical Guidelines for Multidisciplinary Spine Care: Diagnosis & Treatment of Low Back Pain 7075 Veterans Blvd Burr Ridge, IL 60527 630-230-3600 www.spine.org © 2020 North American Spine Society 978-1-929988-65-5Diagnosis & Treatment of Low Back Pain | Preface Recommendations were developed based on a specific definition, inclusion/exclusion criteria, and the resulting literature which excluded conditions such as presence (...) of a neurological deficit or leg pain experienced below the knee, among others. Given the exclusion criteria, these guideline rec- ommendations address a subset of low back pain care as opposed to low back pain in its entirety. This clinical guideline is not intended to be a fixed treatment protocol; it is anticipated that there will be patients who require more or less treatment than what is outlined. This clinical guideline should not be construed as including all proper methods of care or excluding other

2020 North American Spine Society

65. Antibiotic Use for the Urgent Management of Dental Pain and Intra-oral Swelling Clinical Practice Guideline Full Text available with Trip Pro

Antibiotic Use for the Urgent Management of Dental Pain and Intra-oral Swelling Clinical Practice Guideline Evidence-based clinical practice guideline on antibiotic use for the urgent management of pulpal- and periapical-related dental pain and intraoral swelling - The Journal of the American Dental Association Email/Username: Password: Remember me Search Terms Search within Search Access provided by Volume 150, Issue 11, Pages 906–921.e12 Evidence-based clinical practice guideline (...) on antibiotic use for the urgent management of pulpal- and periapical-related dental pain and intraoral swelling A report from the American Dental Association x Peter B. Lockhart , DDS , x Malavika P. Tampi Correspondence Address correspondence to Ms. Tampi at Center for Evidence-Based Dentistry, Science Institute, American Dental Association, 211 East Chicago Ave., Chicago, IL 60611 , MPH ∗ , x Malavika P. Tampi Correspondence Address correspondence to Ms. Tampi at Center for Evidence-Based Dentistry

2020 American Dental Association Guidelines

66. Position Statement on the medicinal use of Cannabinoids in Pain Medicine

Position Statement on the medicinal use of Cannabinoids in Pain Medicine Faculty Position Statement on the medicinal use of Cannabinoids in Pain Medicine Update following the publication of NICE Guidance NG144 (11 November 2019) This statement is focused on the issues relating to cannabis derived medicinal products in relation to Pain Medicine. It does not comment on other areas of medical practice or recreational use, which lie outside our remit. The issue of cannabis, its extracts (...) , formulations and synthetics has very much been on the radar of Pain Medicine for many years. The Faculty supports the guidance and conclusions of the NICE guidance NG144. 1 In respect of Pain Medicine, the Faculty is in agreement that whilst these substances have potential for therapeutic use, their safety and efficacy have not yet been established and a strong evidence base is needed as for any properly licenced medicine. We strongly support and look forward to its development. The development of evidence

2020 Faculty of Pain Medicine

67. Comparison of intradermal mesotherapy with systemic therapy in the treatment of low back pain: A prospective randomized study (Abstract)

Comparison of intradermal mesotherapy with systemic therapy in the treatment of low back pain: A prospective randomized study Musculoskeletal pain such as low back pain (LBP) are routinely encountered in the ED and contribute to ED overcrowding. The aim of our study was to compare the efficiency of mesotherapy with systemic therapy in pain control in patients with lumbar disk herniation.We conducted this prospective parallel randomized controlled trial with the patients admitted (...) to the emergency department with low back pain related to herniated lumbar disk. Mesotherapy was performed to one group, while intravenous dexketoprofen was administered to the control group. Changes in pain intensity at 15th minute, 30th minute, 60th minute and 24th hours after treatment using Visual Analogue Scale (VAS), need to use analgesic drug within 24 h after treatment, and adverse effect of the treatment methods were compared between groups.The decreases in pain intensity were statistically

2020 EvidenceUpdates

68. Atomized intranasal vs intravenous fentanyl in severe renal colic pain management: A randomized single-blinded clinical trial

Atomized intranasal vs intravenous fentanyl in severe renal colic pain management: A randomized single-blinded clinical trial Atomized Intranasal vs Intravenous Fentanyl in Severe Renal Colic Pain Management: A Randomized Single-Blinded Clinical Trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Welcome to the new PubMed. For legacy PubMed go to . Clipboard, Search History, and several other advanced features (...) a collection: Unable to load your collection due to an error Add Cancel Add to My Bibliography My Bibliography Unable to load your delegates due to an error Add Cancel Actions Cite Share Permalink Copy Page navigation Am J Emerg Med Actions , 158483 2019 Oct 23 [Online ahead of print] Atomized Intranasal vs Intravenous Fentanyl in Severe Renal Colic Pain Management: A Randomized Single-Blinded Clinical Trial , , Affiliations Expand Affiliations 1 Department of Emergency Medicine, Kerman University

2020 EvidenceUpdates

69. Effect Of Peppermint Essence On The Pain And Anxiety Caused By Intravenous Catheterization In Cardiac Patients: A Randomized Controlled Trial Full Text available with Trip Pro

Effect Of Peppermint Essence On The Pain And Anxiety Caused By Intravenous Catheterization In Cardiac Patients: A Randomized Controlled Trial The effects of the peppermint essence on the pain and anxiety caused by intravenous catheterization have not been studied yet. The aim of this study was to determine effect of inhaling peppermint essence on the pain and anxiety.In this study, 80 cardiac patients were selected through convenient sampling and randomly allocated to aromatherapy and control (...) groups. Data gathering tools were numeric pain rating scale and visual analogue scale for anxiety. The aromatherapy and control groups received inhaled aromatherapy with peppermint essence and distilled water, respectively.Mean severity of the pain in the aromatherapy and control groups was 2.95±0.98 and 3.42±1.33, respectively. The difference was statistically significant (p=0.048). The mean score of anxiety before the intervention in the aromatherapy and control groups was 3.75±1.08 and 4.70±1.43

2020 EvidenceUpdates

70. Effect of Early Surgery vs Endoscopy-First Approach on Pain in Patients With Chronic Pancreatitis: The ESCAPE Randomized Clinical Trial. (Abstract)

Effect of Early Surgery vs Endoscopy-First Approach on Pain in Patients With Chronic Pancreatitis: The ESCAPE Randomized Clinical Trial. For patients with painful chronic pancreatitis, surgical treatment is postponed until medical and endoscopic treatment have failed. Observational studies have suggested that earlier surgery could mitigate disease progression, providing better pain control and preserving pancreatic function.To determine whether early surgery is more effective than the endoscopy (...) -first approach in terms of clinical outcomes.The ESCAPE trial was an unblinded, multicenter, randomized clinical superiority trial involving 30 Dutch hospitals participating in the Dutch Pancreatitis Study Group. From April 2011 until September 2016, a total of 88 patients with chronic pancreatitis, a dilated main pancreatic duct, and who only recently started using prescribed opioids for severe pain (strong opioids for ≤2 months or weak opioids for ≤6 months) were included. The 18-month follow-up

2020 JAMA

71. Nerve Blocks for Management of Pain Following Hip Fracture

Nerve Blocks for Management of Pain Following Hip Fracture Nerve Blocks for Management of Pain Following Hip Fracture | Emergency Medicine | Washington University in St. Louis Open Menu Back Close Menu Search for: Loading... Welcome Our Team Sections Education Alumni Research ECRC Journal Club Events Jermyn Lectures Open Search Vignette You’re moonlighting in an austere emergency department, and the night has been relatively benign except for your poor 79-year-old severely demented patient who (...) suffered an isolated mid-shaft femur fracture from a mechanical fall earlier today. Unfortunately, the patient is also morbidly obese and has OSA requiring CPAP at night when sleeping. The patient is miserable and is now making your staff miserable, howling out in pain with every breath. Opioids aren’t touching the searing pain, and now you’re worried about potential respiratory complications from too much of a good thing. Your off-going partner in crime mentions doing a “ ” and everyone lets out

2020 Washington University Emergency Medicine Journal Club

72. Clinical phenotypes and classification algorithm for complex regional pain syndrome

Clinical phenotypes and classification algorithm for complex regional pain syndrome Clinical Phenotypes and Classification Algorithm for Complex Regional Pain Syndrome - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Welcome to the new PubMed. For legacy PubMed go to . Clipboard, Search History, and several other advanced features are temporarily unavailable. National Institutes of Health U.S. National Library of Medicine (...) Bibliography My Bibliography Unable to load your delegates due to an error Add Cancel Actions Cite Share Permalink Copy Page navigation Neurology Actions , 94 (4), e357-e367 2020 Jan 28 Clinical Phenotypes and Classification Algorithm for Complex Regional Pain Syndrome , , , , , , , Affiliations Expand Affiliations 1 From the Department of Neurology (V.D., M.S.H., F.E.-L., F.B.), University Medical Center of the Johannes Gutenberg University Mainz; Departments of Anesthesiology (H.L.R.) and Neurology (C.S

2020 EvidenceUpdates

73. Electrocatheter-mediated High-voltage Pulsed Radiofrequency of the Dorsal Root Ganglion in the Treatment of Chronic Lumbosacral Neuropathic Pain: A Randomized Controlled Study Full Text available with Trip Pro

Electrocatheter-mediated High-voltage Pulsed Radiofrequency of the Dorsal Root Ganglion in the Treatment of Chronic Lumbosacral Neuropathic Pain: A Randomized Controlled Study Electrocatheter-mediated High-voltage Pulsed Radiofrequency of the Dorsal Root Ganglion in the Treatment of Chronic Lumbosacral Neuropathic Pain: A Randomized Controlled Study - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Welcome to the new PubMed (...) to an existing collection Name your collection: Name must be less than 100 characters Choose a collection: Unable to load your collection due to an error Add Cancel Add to My Bibliography My Bibliography Unable to load your delegates due to an error Add Cancel Actions Cite Share Permalink Copy Page navigation Clin J Pain Actions , 36 (1), 25-33 Jan 2020 Electrocatheter-mediated High-voltage Pulsed Radiofrequency of the Dorsal Root Ganglion in the Treatment of Chronic Lumbosacral Neuropathic Pain

2020 EvidenceUpdates

74. Efficacy of bilateral erector spinae plane block in the management of pain: current insights Full Text available with Trip Pro

Efficacy of bilateral erector spinae plane block in the management of pain: current insights Efficacy of Bilateral Erector Spinae Plane Block in the Management of Pain: Current Insights - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Welcome to the new PubMed. For legacy PubMed go to . Clipboard, Search History, and several other advanced features are temporarily unavailable. National Institutes of Health U.S. National (...) Add to My Bibliography My Bibliography Unable to load your delegates due to an error Add Cancel Actions Cite Share Permalink Copy Page navigation J Pain Res Actions , 12, 2597-2613 2019 Aug 27 eCollection 2019 Efficacy of Bilateral Erector Spinae Plane Block in the Management of Pain: Current Insights , , , Affiliations Expand Affiliations 1 Department of Anesthesiology and Reanimation, Faculty of Medicine, Maltepe University, Istanbul, Turkey. 2 Department of Anaesthesiology and Reanimation

2020 EvidenceUpdates

75. Multimodal opioid-sparing postoperative pain regimen compared with the standard postoperative pain regimen in vaginal pelvic reconstructive surgery: a multicenter randomized controlled trial

Multimodal opioid-sparing postoperative pain regimen compared with the standard postoperative pain regimen in vaginal pelvic reconstructive surgery: a multicenter randomized controlled trial Multimodal Opioid-Sparing Postoperative Pain Regimen Compared With the Standard Postoperative Pain Regimen in Vaginal Pelvic Reconstructive Surgery: A Multicenter Randomized Controlled Trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set (...) to Collections Create a new collection Add to an existing collection Name your collection: Name must be less than 100 characters Choose a collection: Unable to load your collection due to an error Add Cancel Add to My Bibliography My Bibliography Unable to load your delegates due to an error Add Cancel Actions Cite Share Permalink Copy Page navigation Am J Obstet Gynecol Actions , 221 (5), 511.e1-511.e10 Nov 2019 Multimodal Opioid-Sparing Postoperative Pain Regimen Compared With the Standard Postoperative

2020 EvidenceUpdates

76. A randomized, double-blind, placebo-controlled trial of onabotulinumtoxin A trigger point injections for myofascial pelvic pain

A randomized, double-blind, placebo-controlled trial of onabotulinumtoxin A trigger point injections for myofascial pelvic pain A Randomized, Double-Blind, Placebo-Controlled Trial of Onabotulinumtoxin A Trigger Point Injections for Myofascial Pelvic Pain - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Welcome to the new PubMed. For legacy PubMed go to . Clipboard, Search History, and several other advanced features (...) a collection: Unable to load your collection due to an error Add Cancel Add to My Bibliography My Bibliography Unable to load your delegates due to an error Add Cancel Actions Cite Share Permalink Copy Page navigation Am J Obstet Gynecol Actions , 221 (5), 517.e1-517.e9 Nov 2019 A Randomized, Double-Blind, Placebo-Controlled Trial of Onabotulinumtoxin A Trigger Point Injections for Myofascial Pelvic Pain , , , , Affiliations Expand Affiliations 1 Division of Urogynecology, Department of Obstetrics

2020 EvidenceUpdates

77. Subacromial decompression surgery for adults with shoulder pain Full Text available with Trip Pro

Subacromial decompression surgery for adults with shoulder pain Subacromial decompression surgery for adults with shoulder pain: a clinical practice guideline | The BMJ Intended for healthcare professionals Username * Password * Edition: Search form Search Search Subacromial... Subacromial decompression surgery for adults with shoulder pain: a clinical practice guideline (Published 06 February 2019) Cite this as: BMJ 2019;364:l294 Visual summary of recommendation or Subacromial decompression (...) surgery Nonoperative management only Arthroscopic subacromial decompression plus nonoperative management Including guided physical therapy, exercise programmes, NSAIDs, and steroid injections Interventions compared Recommendation Population Adults with shoulder pain for more than 3 months Does not apply to patients with: Including: Traumatic shoulder pain Subacromial pain syndrome (SAPS) Rotator cuff disease (RCD) Other differential diagnoses We recommend against subacromial decompression surgery More

2019 BMJ Rapid Recommendations

78. Inhaled Methoxyflurane Provides Greater Analgesia and Faster Onset of Action Versus Standard Analgesia in Patients With Trauma Pain: InMEDIATE: A Randomized Controlled Trial in Emergency Departments Full Text available with Trip Pro

Inhaled Methoxyflurane Provides Greater Analgesia and Faster Onset of Action Versus Standard Analgesia in Patients With Trauma Pain: InMEDIATE: A Randomized Controlled Trial in Emergency Departments The objective of the InMEDIATE study was to evaluate the change in intensity of traumatic pain over the first 20 min in adult patients treated with methoxyflurane versus standard analgesic treatment in Spain. This the first randomized, active-controlled, multicenter trial of methoxyflurane (...) in the emergency setting in Europe.This was a randomized, controlled study that enrolled adult patients with acute moderate to severe (score ≥4 on the 11-point Numeric Rating Scale) trauma-associated pain in 14 Spanish emergency departments. Patients were randomized 1:1 to methoxyflurane (up to 2×3 mL) or standard analgesic treatment. Coprimary endpoints were the change from baseline in Numeric Rating Scale pain intensity score during the first 20 minutes of treatment and time to first pain relief.Three

2019 EvidenceUpdates

79. Effects of open-label placebo on pain, functional disability, and spine mobility in patients with chronic back pain: a randomized controlled trial (Abstract)

Effects of open-label placebo on pain, functional disability, and spine mobility in patients with chronic back pain: a randomized controlled trial Chronic back pain (CBP) is a major global health problem, while its treatment is hampered by a lack of efficacy and restricted safety profile of common frontline therapies. The present trial aims to determine whether a 3-week open-label placebo treatment reduces pain intensity and subjective and objective functional disability in patients with CBP (...) . This randomized controlled trial, following a pretest-posttest design, enrolled 127 patients with CBP (pain duration >12 weeks) from the Back Pain Center, Neurology, University Hospital Essen, Germany. Patients randomized to the open-label placebo group received a 3-week open-label placebo treatment. Patients in the treatment as usual (TAU) group received no intervention. Both groups continued TAU. Primary outcome was the change in pain intensity. Secondary outcomes included patient-reported functional

2019 EvidenceUpdates

80. Diamorphine hydrochloride (Ayendi) - acute severe nociceptive pain in children and adolescents

Diamorphine hydrochloride (Ayendi) - acute severe nociceptive pain in children and adolescents Final Appraisal Recommendation Advice No: 1719 – November 2019 Diamorphine hydrochloride (Ayendi ® ) 720 microgram/actuation and 1600 microgram/actuation Nasal Spray Limited submission by Wockhardt UK Ltd In reaching the above recommendation AWMSG has taken account of the appraisal documentation prepared by the AWMSG Secretariat (reference number 2406), which includes the AWMSG Secretariat Assessment (...) nociceptive pain in children and adolescents 2 to 15 years of age in a hospital setting. Ayendi ® nasal spray should be administered in the emergency setting by practitioners experienced in the administration of opioids in children and with the appropriate monitoring. Statement of use: No part of this recommendation may be reproduced without the whole recommendation being quoted in full and cited as: All Wales Medicines Strategy Group Final Appraisal Recommendation – 1719: Diamorphine hydrochloride

2019 All Wales Medicines Strategy Group