Latest & greatest articles for pain

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on pain or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on pain and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

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Top results for pain

3301. The efficacy of phytodolor for the treatment of musculoskeletal pain: a systematic review of randomized clinical trials

The efficacy of phytodolor for the treatment of musculoskeletal pain: a systematic review of randomized clinical trials The efficacy of phytodolor for the treatment of musculoskeletal pain: a systematic review of randomized clinical trials The efficacy of phytodolor for the treatment of musculoskeletal pain: a systematic review of randomized clinical trials Ernst E Authors' objectives To assess the efficacy of phytodolor for the treatment of musculoskeletal pain. Searching Computerised (...) literature searches were performed to identify all trials of herbal remedies used for treating musculoskeletal pain. Databases searched included: MEDLINE, EMBASE, CISCOM, and the Cochrane Library, all from inception to October 1997. In addition, review articles and books on phytotherapy/herbalism and the author's files were searched for relevant publications. Manufacturers were contacted and asked to contribute published and unpublished trials. Other experts in the field were asked for further relevant

2000 DARE.

3302. Is acupuncture effective for the treatment of chronic pain: a systematic review

Is acupuncture effective for the treatment of chronic pain: a systematic review Is acupuncture effective for the treatment of chronic pain: a systematic review Is acupuncture effective for the treatment of chronic pain: a systematic review Ezzo J, Berman B, Hadhazy V A, Jadad A R, Lao L, Singh B B Authors' objectives To assess the effectiveness of acupuncture as a treatment for chronic pain within the context of the methodological quality of the studies. Searching MEDLINE (1996 to 1999) and two (...) specialised complementary medicine databases, the Cochrane Complementary Medicine Field trials registry and the University of Maryland CAMPAIN (Complementary and Alternative Medicine in Pain) were searched. The terms 'acupuncture'. 'alternative medicine', 'electroacupuncture', 'moxibustion', 'injections, intramuscular', 'Medicine, Traditional Chinese' were exploded as MeSH terms and searched as textwords. 'Trigger point therapy;' and 'auriculotherapy' were searched as textwords only. The search

2000 DARE.

3303. Complementary and alternative medicine in the management of pain, dyspnea, and nausea and vomiting near the end of life: a systematic review

Complementary and alternative medicine in the management of pain, dyspnea, and nausea and vomiting near the end of life: a systematic review Complementary and alternative medicine in the management of pain, dyspnea, and nausea and vomiting near the end of life: a systematic review Complementary and alternative medicine in the management of pain, dyspnea, and nausea and vomiting near the end of life: a systematic review Pan C X, Morrison R S, Ness J, Fugh-Berman A, Leipzig R M Authors (...) ' objectives To assess the efficacy of complementary and alternative medicine (CAM) modalities in treating pain, dyspnoea, and nausea and vomiting in patients near the end of life. Searching The databases searched were MEDLINE (from 1966 to 1998), CINAHL (from 1982 to 1997), Cancerlit (from 1993 to 1998), AIDSLINE (from 1980 to 1998), Social Work Abstracts (from 1977 to 1997) and PsycLIT (from 1967 to 1998). Full details of the search terms used for each database were given. The bibliographies

2000 DARE.

3304. Treatment of pain or fever with paracetamol (acetaminophen) in the alcoholic patient: a systematic review

Treatment of pain or fever with paracetamol (acetaminophen) in the alcoholic patient: a systematic review Treatment of pain or fever with paracetamol (acetaminophen) in the alcoholic patient: a systematic review Treatment of pain or fever with paracetamol (acetaminophen) in the alcoholic patient: a systematic review Dart R C, Kuffner E K, Rumack B H Authors' objectives To evaluate whether the administration of therapeutic doses of paracetamol cause hepatic injury in the alcoholic patient (...) . Overall, the authors' conclusions appear to follow from the data presented. Readers should take note of the different outcomes from the more reliable findings in the Class I and II studies, compared with the lower-quality non-randomised and non-controlled Class III case reports. Implications of the review for practice and research Practice: The authors state that during chronic treatment of pain, paracetamol may be preferred in the compliant alcoholic patient owing to the adverse effects associated

2000 DARE.

3305. Evidence-based data on pain relief with antidepressants

Evidence-based data on pain relief with antidepressants Evidence-based data on pain relief with antidepressants Evidence-based data on pain relief with antidepressants Fishbain D Authors' objectives To systematically review the evidence for antidepressant pain efficacy, including clinical studies and recent meta-analyses (MA) studies. A secondary objective was to review the consistency of pain efficacy evidence for different pain syndromes, to determine what evidence, if any, exists (...) for the superiority of subgroups of antidepressants and to propose some reasons why conflicting conclusions about pain efficacy have previously been reported in the literature. Searching MEDLINE, PsycINFO, Science Citation Index and PDQ databases were reviewed. The following MeSH terms were used: meta-analysis (MA) and pain, and antidepressants and pain, with each heading being exploded for all subheadings. All databases were searched from 1966 to 1999, except for the Science Citation Index that was searched from

2000 DARE.

3306. Teasing apart quality and validity in systematic reviews: an example from acupuncture trials in chronic neck and back pain

Teasing apart quality and validity in systematic reviews: an example from acupuncture trials in chronic neck and back pain Teasing apart quality and validity in systematic reviews: an example from acupuncture trials in chronic neck and back pain Teasing apart quality and validity in systematic reviews: an example from acupuncture trials in chronic neck and back pain Smith L A, Oldman A D, McQuay H J, Moore R A Authors' objectives To assess the analgesic efficacy and the adverse effects (...) of acupuncture compared with placebo for back and neck pain. To develop a new tool, the Oxford Pain Validity Scale (OPVS), to measure validity of findings from randomised controlled trials (RCTs), and to enable ranking of trial findings according to validity within qualitative reviews. Searching Different search strategies were used to search the following sources: MEDLINE from 1966 to August 1998; EMBASE from 1980 to August 1998; CINAHL from 1982 to 1998; PsycLIT from 1982 to 1998; PubMed in 1998

2000 DARE.

3307. Cost effectiveness analysis of intravenous ketorolac and morphine for treating pain after limb injury: double blind randomised controlled trial

Cost effectiveness analysis of intravenous ketorolac and morphine for treating pain after limb injury: double blind randomised controlled trial Cost effectiveness analysis of intravenous ketorolac and morphine for treating pain after limb injury: double blind randomised controlled trial Cost effectiveness analysis of intravenous ketorolac and morphine for treating pain after limb injury: double blind randomised controlled trial Rainer T H, Jacobs P, Ng Y C, Cheung N K, Tam M, Lam P K, Wong R (...) , Cocks R A Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Pain relief/management for patients with limb injuries. Specifically intravenous ketorolac and morphine were examined. Type of intervention Treatment; Pain relief. Economic

2000 NHS Economic Evaluation Database.

3308. An evidence-based medicine approach to the treatment of endometriosis-associated chronic pelvic pain: placebo-controlled studies

An evidence-based medicine approach to the treatment of endometriosis-associated chronic pelvic pain: placebo-controlled studies An evidence-based medicine approach to the treatment of endometriosis-associated chronic pelvic pain: placebo-controlled studies An evidence-based medicine approach to the treatment of endometriosis-associated chronic pelvic pain: placebo-controlled studies Howard F M Authors' objectives To assess the efficacy of treatment of endometriosis-associated chronic pelvic (...) pain. Searching MEDLINE was searched from 1976 to 1998 for articles published in the English language, using a combination of the following MeSH and textwords: 'endometriosis', 'pelvic pain', 'treatment'. Additional studies were located by examining the references from the identified studies, and by contacting the authors of selected studies. Study selection Study designs of evaluations included in the review Placebo-controlled randomised clinical trials (RCTs) were eligible if they scored at least

2000 DARE.

3309. Single-dose ketorolac and pethidine in acute postoperative pain: systematic review with meta-analysis

Single-dose ketorolac and pethidine in acute postoperative pain: systematic review with meta-analysis Single-dose ketorolac and pethidine in acute postoperative pain: systematic review with meta-analysis Single-dose ketorolac and pethidine in acute postoperative pain: systematic review with meta-analysis Smith L A, Carroll D, Edwards J E, Moore R A, McQuay H J Authors' objectives To examine the postoperative analgesic efficacy and adverse effects of single doses, injected or oral, of pethidine (...) and ketorolac compared with placebo. Searching The following electronic databases were searched: MEDLINE, (1966 to July 1998), EMBASE (1980 to 1998), the Cochrane Library (1998 issue 2) and the Oxford pain relief database (1950 to 1994). Broad free text searches with no language restrictions were undertaken using terms which are listed in the review. Reference lists of retrieved reports were searched for additional articles. Roche Products Ltd UK were contacted for ketorolac reports. Authors of articles

2000 DARE.

3310. Prevention of pain on injection with propofol: a quantitative systematic review

Prevention of pain on injection with propofol: a quantitative systematic review Prevention of pain on injection with propofol: a quantitative systematic review Prevention of pain on injection with propofol: a quantitative systematic review Picard P, Tramer M R Authors' objectives To test, with the best available evidence, the relative efficacy of analgesic interventions that have been used to prevent pain caused by propofol injection. Searching MEDLINE (via Datastar and PubMed from 1966 (...) to September 1999), Cochrane Library (1999, issue 3) and EMBASE (from 1982 to February 1999) were searched using different strategies but with the free textwords 'propofol', 'pain', 'injection' and 'random', alone and in combination. The search was not restricted to the English language. Additional trials were identified from reference lists of retrieved reports and from review articles on propofol and pain on injection, and by manually searching locally available anaesthetic journals. Study selection

2000 DARE.

3311. Pain after laparoscopic cholecystectomy

Pain after laparoscopic cholecystectomy Pain after laparoscopic cholecystectomy Pain after laparoscopic cholecystectomy Wills V L, Hunt D R Authors' objectives To assess the interventions used to reduce pain after laparoscopic cholecystectomy. Searching MEDLINE was searched from January 1990 to June 1999 using the keywords 'pain', 'cholecystectomy/laparoscopic', 'pneumoperitoneum' and 'laparoscopy'. Bibliographies of retrieved articles were also examined. Although studies reported in any (...) language were eligible, it was not possible to obtain every non-English language article. Study selection Study designs of evaluations included in the review Randomised controlled trials (RCTs) were eligible for inclusion. Specific interventions included in the review Studies comparing pain-reducing interventions with control interventions were eligible. The following types of interventions were included. 1. Use of non-steroidal anti-inflammatory drugs (NSAIDs): NSAIDs (diclofenac, ketorolac, dipyrone

2000 DARE.

3312. Local anesthetic infiltration for postoperative pain relief after laparoscopy: a qualitative and quantitative systematic review of intraperitoneal, port-site infiltration and mesosalpinx block

Local anesthetic infiltration for postoperative pain relief after laparoscopy: a qualitative and quantitative systematic review of intraperitoneal, port-site infiltration and mesosalpinx block Local anesthetic infiltration for postoperative pain relief after laparoscopy: a qualitative and quantitative systematic review of intraperitoneal, port-site infiltration and mesosalpinx block Local anesthetic infiltration for postoperative pain relief after laparoscopy: a qualitative and quantitative (...) systematic review of intraperitoneal, port-site infiltration and mesosalpinx block Moiniche S, Jorgensen H, Wetterslev J, Dahl J B Authors' objectives To evaluate the effects of peripherally applied local anaesthetics (intraperitoneal, installation, trocar- and port-site wound infiltration, and visceral infiltration/application) on postoperative pain in patients undergoing laparoscopic surgery, by using evidence from all double-blinded, relevant randomised controlled trials. Searching The Cochrane

2000 DARE.

3313. Application of surface electromyography in the assessment of low back pain: a literature review

Application of surface electromyography in the assessment of low back pain: a literature review Application of surface electromyography in the assessment of low back pain: a literature review Application of surface electromyography in the assessment of low back pain: a literature review Mohseni-Bandpei M A, Watson M J, Richardson B Authors' objectives To assess the clinical application of surface electromyography (SEMG) in the assessment of people with chronic lower-back pain (LBP). Searching (...) . The test positions included: sitting with and without back support; standing; trunk flexion, extension or rotation; stooping; walking; isometric trunk testing; isometric extension; prone position; lifting two-pound disks; and unsupported trunk holding test. Reference standard test against which the new test was compared The reference standard was not explicitly stated but appears to have been a clinical diagnosis (no details provided) of lower-back pain. Participants included in the review Studies

2000 DARE.

3314. Samarium-153-lexidronam for bone pain due to skeletal metastases

Samarium-153-lexidronam for bone pain due to skeletal metastases Samarium-153-lexidronam for bone pain due to skeletal metastases Samarium-153-lexidronam for bone pain due to skeletal metastases Medicare Services Advisory Committee Authors' objectives To assess the current evidence for samarium (Sm)-153-lexidronam injection for the treatment of bone pain in patients with skeletal metastases. Searching MEDLINE, HealthSTAR, TOXLINE, Cancerlit, Pascal, BIOSIS Previews, one of the Derwent databases (...) , SciSearch, Elsevier BIOBASE, EMBASE, Current Contents and the Cochrane Library were searched between 1966 and September 1998. The search terms included 'samarium-153', 'samarium-153 EDTMP', 'strontium', 'strontium-89' and 'bone pain due to skeletal metastases', 'palliative therapy' and 'randomised controlled trial'. Study selection Study designs of evaluations included in the review RCTs (phase III) were included for the assessment of effectiveness, while phase I or II trials were included

2000 DARE.

3315. Pre-insertion local anesthesia at the trocar site improves peri-operative pain and decreases costs in laparoscopic cholecystectomy

Pre-insertion local anesthesia at the trocar site improves peri-operative pain and decreases costs in laparoscopic cholecystectomy Pre-insertion local anesthesia at the trocar site improves peri-operative pain and decreases costs in laparoscopic cholecystectomy Pre-insertion local anesthesia at the trocar site improves peri-operative pain and decreases costs in laparoscopic cholecystectomy Hasaniya N, Zayed F, Faiz H, Severino R Record Status This is a critical abstract of an economic (...) was observed. The method of randomisation was not reported. Analysis of effectiveness All of the patients included in the study were accounted for in the analysis of effectiveness (intention to treat analysis). The health outcomes used in the study were: the estimated blood loss, operative time, bile culture, and postoperative pain at the trocar site, evaluated at 4 and 24 hours from surgery using a numerical rating pain scale. The two groups were reported to be comparable at baseline in terms of age

2000 NHS Economic Evaluation Database.

3316. Economic analysis of terminal care for patients with malignant osteolytic bone disease and pain treated with pamidronate

Economic analysis of terminal care for patients with malignant osteolytic bone disease and pain treated with pamidronate Economic analysis of terminal care for patients with malignant osteolytic bone disease and pain treated with pamidronate Economic analysis of terminal care for patients with malignant osteolytic bone disease and pain treated with pamidronate Gessner U, Koeberle D, Thuerlimann B, Bacchus L, Horisberger B Record Status This is a critical abstract of an economic evaluation (...) that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The use of pamidronate, 60 or 90 mg intravenously (i.v.), for palliation of patients with malignant osteolytic bone disease and pain. Type of intervention Palliative care. Economic study type Cost-effectiveness study. Study population The study population

2000 NHS Economic Evaluation Database.

3317. Should noncardiac chest pain be treated empirically? A cost-effectiveness analysis

Should noncardiac chest pain be treated empirically? A cost-effectiveness analysis Should noncardiac chest pain be treated empirically? A cost-effectiveness analysis Should noncardiac chest pain be treated empirically? A cost-effectiveness analysis Borzecki A M, Pedrosa M C, Prashker M J Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed (...) by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Empirical treatment in patients with non-cardiac chest pain (NCCP). Type of intervention Treatment. Economic study type Cost-effectiveness analysis. Study population An outpatient with chest pain and a normal coronary angiogram. The prototype patient was female and aged 45 to 55 years. Setting Hospital. The economic study was carried out in the USA. Dates to which data relate Effectiveness

2000 NHS Economic Evaluation Database.

3318. Long-term experience with an accelerated protocol for diagnosis of chest pain

Long-term experience with an accelerated protocol for diagnosis of chest pain Long-term experience with an accelerated protocol for diagnosis of chest pain Long-term experience with an accelerated protocol for diagnosis of chest pain Caragher T E, Fernandez B B, Barr L A Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed (...) critical assessment on the reliability of the study and the conclusions drawn. Health technology The use of an accelerated protocol for chest pain triage. The accelerated chest pain protocol (CPP) used medical history, electrocardiogram and the biomarkers creatine kinase (CK-MB), total CK, myoglobin and cardiac troponin I (cTnI) to rule acute coronary syndrome (ACS) in or out in a 9-hour algorithm. A multidisciplinary team involving 4 nurses, 4 physicians and 1 clinical laboratory scientist defined

2000 NHS Economic Evaluation Database.

3319. Adjuvant physical therapy versus occupational therapy in patients with reflex sympathetic dystrophy/complex regional pain syndrome type I

Adjuvant physical therapy versus occupational therapy in patients with reflex sympathetic dystrophy/complex regional pain syndrome type I Adjuvant physical therapy versus occupational therapy in patients with reflex sympathetic dystrophy/complex regional pain syndrome type I Adjuvant physical therapy versus occupational therapy in patients with reflex sympathetic dystrophy/complex regional pain syndrome type I Oerlemans H M, Oostendorp R A, de Boo T, van der Laan L, Severens J L, Goris J (...) regional pain syndrome Type I. Type of intervention Rehabilitation. Economic study type Cost-effectiveness analysis. Study population The study population comprised patients with RSD, excluding those with a peripheral nerve lesion. RSD was diagnosed according to the criteria published by Veldman et al. (see Other Publications of Related Interest. Patients were included if they met the following inclusion criteria: they had RSD of one upper extremity with a duration of less than 1 year; complete

2000 NHS Economic Evaluation Database.

3320. Intrathecal pumps for giving opioids in chronic pain: a systematic review

Intrathecal pumps for giving opioids in chronic pain: a systematic review Intrathecal pumps for giving opioids in chronic pain: a systematic review Intrathecal pumps for giving opioids in chronic pain: a systematic review Williams J E, Louw G, Towlerton G Authors' objectives To review the evidence on the use of intrathecal pump systems for administering opioids in patients with chronic pain in order to draw conclusions regarding the effectiveness, side-effects and cost-effectiveness (...) cancer or non-cancer resistant pain problems, or those who experienced unacceptable side-effects from the use of high-dose opioids delivered by conventional routes, were eligible for inclusion in the review. Participants with acute pain were not eligible for inclusion. Outcomes assessed in the review Studies that included efficacy measures (visual analogue scale scores, verbal rating scale scores, McGill Pain Questionnaire scores, Brief Pain Inventory scale scores, range of movement, ability

2000 DARE.