Latest & greatest articles for geriatrics

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Top results for geriatrics

41. Comparison of efficacy nebulized fentanyl with intravenous ketorolac for renal colic in patients over 12 years old

Comparison of efficacy nebulized fentanyl with intravenous ketorolac for renal colic in patients over 12 years old Comparison of Efficacy Nebulized Fentanyl With Intravenous Ketorolac for Renal Colic in Patients Over 12 Years Old - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. National Institutes of Health National Library (...) displayed: Create RSS Cancel RSS Link Copy Actions Cite Share Permalink Copy Page navigation Am J Emerg Med Actions . 2020 Apr 21;S0735-6757(20)30257-6. doi: 10.1016/j.ajem.2020.04.053. Online ahead of print. Comparison of Efficacy Nebulized Fentanyl With Intravenous Ketorolac for Renal Colic in Patients Over 12 Years Old , , , Affiliations Expand Affiliations 1 Clinical Research Development Center of Taleghani, Kermanshah University of Medical Sciences, Kermanshah, Iran. 2 Department of Emergency

2020 EvidenceUpdates

42. Dynamic statistical model for predicting the risk of death among older Chinese people, using longitudinal repeated measures of the frailty index: a prospective cohort study

predictive ability. Conclusions: We developed a dynamic prediction model that was able to update predictions of the risk of death as updated measurements of FI became available. This model could be used to estimate the risk of death in individuals aged >65 years. Keywords: dynamic statistical prediction model; frailty index; older people; people over 65 years; prospective cohort study; risk of death. © The Author(s) 2020. Published by Oxford University Press on behalf of the British Geriatrics Society (...) a file for external citation management software Create file Cancel Your RSS Feed Name of RSS Feed: Number of items displayed: Create RSS Cancel RSS Link Copy Actions Cite Share Permalink Copy Page navigation Age Ageing Actions . 2020 May 4;afaa056. doi: 10.1093/ageing/afaa056. Online ahead of print. Dynamic Statistical Model for Predicting the Risk of Death Among Older Chinese People, Using Longitudinal Repeated Measures of the Frailty Index: A Prospective Cohort Study , , , , , , , , , Affiliations

2020 EvidenceUpdates

43. Use of sodium-glucose cotransporter-2 inhibitors and risk of acute kidney injury in older adults with diabetes: a population-based cohort study Full Text available with Trip Pro

) after the initiation of sodium-glucose cotransporter-2 (SGLT2) inhibitors. Our objective was to quantify the 90-day risk of AKI in older adults after initiation of SGLT2 inhibitors in routine clinical practice. Methods: We conducted a population-based retrospective cohort study in Ontario, Canada, involving adults with diabetes who were aged 66 years or older and who were newly dispensed either an SGLT2 inhibitor or a dipeptidyl peptidase-4 (DPP4) inhibitor in an outpatient setting between 2015 (...) Use of sodium-glucose cotransporter-2 inhibitors and risk of acute kidney injury in older adults with diabetes: a population-based cohort study Use of Sodium-Glucose cotransporter-2 Inhibitors and Risk of Acute Kidney Injury in Older Adults With Diabetes: A Population-Based Cohort Study - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily

2020 EvidenceUpdates

44. Augmenting Computerized Cognitive Training With Vortioxetine for Age-Related Cognitive Decline: A Randomized Controlled Trial

links Cite Erratum in Am J Psychiatry. 2020 Jun 1;177(6):556. doi: 10.1176/appi.ajp.2020.1776correction. Am J Psychiatry. 2020. PMID: 32475135 No abstract available. Abstract Objective: Age-related cognitive decline, the deterioration in functions such as memory and executive function, is faced by most older adults and affects function and quality of life. No approved treatments exist for age-related cognitive decline. Computerized cognitive training has been shown to provide consistent albeit (...) modest improvements in cognitive function as measured by neuropsychological testing. Vortioxetine, an antidepressant medication, has putative procognitive and proneuroplastic properties and therefore may be able to augment cognitive training. In this placebo-controlled study, the authors tested the cognitive benefits of vortioxetine added to cognitive training for adults age 65 or older with age-related cognitive decline. Methods: After a 2-week lead-in period of cognitive training, 100 participants

2020 EvidenceUpdates

45. Effects of Geriatric Interdisciplinary Home Rehabilitation on Independence in Activities of Daily Living in Older People With Hip Fracture: A Randomized Controlled Trial Full Text available with Trip Pro

interdisciplinary home rehabilitation for older people with hip fracture on independence in activities of daily living (ADL) compared with inhospital geriatric care according to a multifactorial rehabilitation program. Design: Planned analysis of a randomized controlled trial with 3- and 12-month follow-ups. Setting: Geriatric ward, ordinary housing, and residential care facilities. Participants: Of 466 people screened for eligibility, participants (N=205) with acute hip fracture, aged 70 years or older (...) Effects of Geriatric Interdisciplinary Home Rehabilitation on Independence in Activities of Daily Living in Older People With Hip Fracture: A Randomized Controlled Trial Effects of Geriatric Interdisciplinary Home Rehabilitation on Independence in Activities of Daily Living in Older People With Hip Fracture: A Randomized Controlled Trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History

2020 EvidenceUpdates

46. 2019 EULAR points to consider for non-physician health professionals to prevent and manage fragility fractures in adults 50 years or older Full Text available with Trip Pro

Sciences, University of Southampton, Southampton, UK. 2 Department Care I, Musculoskeletal System & Neurology, Dutch National Health Care Institute, Diemen, The Netherlands. 3 EULAR Standing Committee of People with Arthritis/Rheumatism in Europe (PARE), Zurich, Switzerland. 4 EULAR Young PARE, Zurich, Switzerland. 5 Slovak League Against Rheumatism, Piestany, Slovakia. 6 Medicine for Older People, University Hospital Southampton NHS Foundation Trust, Southampton, UK. 7 Department of Rheumatology (...) of Health Sciences, University of Southampton, Southampton, UK. 2 Department Care I, Musculoskeletal System & Neurology, Dutch National Health Care Institute, Diemen, The Netherlands. 3 EULAR Standing Committee of People with Arthritis/Rheumatism in Europe (PARE), Zurich, Switzerland. 4 EULAR Young PARE, Zurich, Switzerland. 5 Slovak League Against Rheumatism, Piestany, Slovakia. 6 Medicine for Older People, University Hospital Southampton NHS Foundation Trust, Southampton, UK. 7 Department

2020 EvidenceUpdates

47. Respiratory rehabilitation in elderly patients with COVID-19: A randomized controlled study Full Text available with Trip Pro

Actions Cite Share Permalink Copy Page navigation Randomized Controlled Trial Complement Ther Clin Pract Actions . 2020 May;39:101166. doi: 10.1016/j.ctcp.2020.101166. Epub 2020 Apr 1. Respiratory Rehabilitation in Elderly Patients With COVID-19: A Randomized Controlled Study , , , , , Affiliations Expand Affiliations 1 Department of Geriatric Center, Hainan General Hospital (Hainan Affiliated Hospital of Hainan Medical University), Haikou, 570311, PR China. 2 Department of General Surgery, Hainan (...) Rehabilitation in Elderly Patients With COVID-19: A Randomized Controlled Study Kai Liu et al. Complement Ther Clin Pract . 2020 May . Free PMC article Show details Complement Ther Clin Pract Actions . 2020 May;39:101166. doi: 10.1016/j.ctcp.2020.101166. Epub 2020 Apr 1. Authors , , , , , Affiliations 1 Department of Geriatric Center, Hainan General Hospital (Hainan Affiliated Hospital of Hainan Medical University), Haikou, 570311, PR China. 2 Department of General Surgery, Hainan General Hospital (Hainan

2020 EvidenceUpdates

48. Strategies For Risk Reduction and Management of Older Adults With Cardiovascular Disease During the COVID-19 Pandemic

Strategies For Risk Reduction and Management of Older Adults With Cardiovascular Disease During the COVID-19 Pandemic Strategies For Risk Reduction and Management of Older Adults With Cardiovascular Disease During the COVID-19 Pandemic - American College of Cardiology ') Search All Types Search or Menu . This article was authored by Nicole M. Orr, MD, FACC , and the Geriatric Cardiology Council. Share via: Clinical Topics: Keywords: Aged, SARS Virus, Angiotensin Receptor Antagonists (...) , Hydroxychloroquine, Mineralocorticoid Receptor Antagonists, Caregivers, Angiotensin-Converting Enzyme Inhibitors, COVID-19, Coronavirus, Coronavirus Infections, Neprilysin, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Neprilysin, Chloroquine, Subacute Care, Social Isolation, Skilled Nursing Facilities, Cardiovascular Diseases > > Strategies For Risk Reduction and Management of Older Adults With Cardiovascular Disease During the COVID-19 Pandemic Heart House 2400 N Street NW Washington, DC 20037 Phone: , ext

2020 American College of Cardiology

49. Community-based health promotion for older adults

and outcomes for people aged over 60 years? 13 Grey Literature 24 Gaps in the evidence 25 Discussion 26 Applicability 28 References 31 Appendix A 35 Appendix B 36 Appendix C 45 Appendix D 46 COMMUNITY-BASED HEALTH PROMOTION FOR OLDER ADULTS APRIL 2019 | SAX INSTITUTE 5 Executive summary Background Older adults who are physically active maintain better health and cognitive function than adults who are not. Evidence-based strategies to increase health and wellbeing among older people are needed (...) Question 1: What community-based programs, that combine physical activity, with other activities addressing key health risk factors, have shown to be effective in improving the health behaviours and outcomes for people aged over 60 years? The evidence check identified 26 papers reporting on 23 different community-based programs for older adults (60+ years) that met the criteria for inclusion in this rapid review. Programs were developed in the United States, Canada, Brazil, several European countries

2020 Sax Institute Evidence Check

50. How might the wellbeing of older people living in the community be supported when shielding and social distancing has been recommended for an extended period of time?

from a bank or post office. Consider action to ensure that older people are not concerned about being able to pay their telephone/broadband bills. Telephone communication providers should consider whether they are able to cap call and internet charges and provide unlimited use for elderly people during this period. What the evidence says We based these suggestions on the following research findings On quality of life older people report value in: ? Being able to manage on their own retaining (...) to meet basic needs o Having material resources to feel comfortable and independent 2 This review looked at qualitative research, in people aged 65 or over who were still living independently, that investigated their views about occupations that enhanced their wellbeing. Authors found that: Solitary occupations are described as positive and highly important to older people’s wellbeing. ? Older people described the need for autonomy in deciding what to do and when to do it; occupations needed

2020 Public Health Wales Observatory Evidence Service

51. Antithrombotic Treatment of Embolic Stroke of Undetermined Source: RE-SPECT ESUS Elderly and Renally Impaired Subgroups Full Text available with Trip Pro

Antithrombotic Treatment of Embolic Stroke of Undetermined Source: RE-SPECT ESUS Elderly and Renally Impaired Subgroups Antithrombotic Treatment of Embolic Stroke of Undetermined Source: RE-SPECT ESUS Elderly and Renally Impaired Subgroups - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. National Institutes of Health National (...) : Number of items displayed: Create RSS Cancel RSS Link Copy Actions Cite Share Permalink Copy Page navigation Stroke Actions . 2020 Jun;51(6):1758-1765. doi: 10.1161/STROKEAHA.119.028643. Epub 2020 May 14. Antithrombotic Treatment of Embolic Stroke of Undetermined Source: RE-SPECT ESUS Elderly and Renally Impaired Subgroups , , , , , , , , , , , , , , , , , , , , , , , Affiliations Expand Affiliations 1 From the Faculty of Medicine, Institute for Medical Informatics, Biometry and Epidemiology

2020 EvidenceUpdates

52. Estimating excess 1-year mortality associated with the COVID-19 pandemic according to underlying conditions and age: a population-based cohort study. Full Text available with Trip Pro

Estimating excess 1-year mortality associated with the COVID-19 pandemic according to underlying conditions and age: a population-based cohort study. The medical, societal, and economic impact of the coronavirus disease 2019 (COVID-19) pandemic has unknown effects on overall population mortality. Previous models of population mortality are based on death over days among infected people, nearly all of whom thus far have underlying conditions. Models have not incorporated information on high-risk (...) by Public Health England guidelines (from March 16, 2020) in individuals aged 30 years or older registered with a practice between 1997 and 2017, using validated, openly available phenotypes for each condition. We estimated 1-year mortality in each condition, developing simple models (and a tool for calculation) of excess COVID-19-related deaths, assuming relative impact (as relative risks [RRs]) of the COVID-19 pandemic (compared with background mortality) of 1·5, 2·0, and 3·0 at differing infection

2020 Lancet

53. Effect of Antihypertensive Medication Reduction vs Usual Care on Short-term Blood Pressure Control in Patients With Hypertension Aged 80 Years and Older: The OPTIMISE Randomized Clinical Trial. (Abstract)

in systolic blood pressure control or adverse events during 12-week follow-up.The Optimising Treatment for Mild Systolic Hypertension in the Elderly (OPTIMISE) study was a randomized, unblinded, noninferiority trial conducted in 69 primary care sites in England. Participants, whose primary care physician considered them appropriate for medication reduction, were aged 80 years and older, had systolic blood pressure lower than 150 mm Hg, and were receiving at least 2 antihypertensive medications were (...) Effect of Antihypertensive Medication Reduction vs Usual Care on Short-term Blood Pressure Control in Patients With Hypertension Aged 80 Years and Older: The OPTIMISE Randomized Clinical Trial. Deprescribing of antihypertensive medications is recommended for some older patients with polypharmacy and multimorbidity when the benefits of continued treatment may not outweigh the harms.This study aimed to establish whether antihypertensive medication reduction is possible without significant changes

2020 JAMA

54. In older adults with acute ischemic stroke, the Clinical Frailty Scale predicted mortality at 28 days. (Abstract)

In older adults with acute ischemic stroke, the Clinical Frailty Scale predicted mortality at 28 days. Evans NR, Wall J, To B, et al. Clinical frailty independently predicts early mortality after ischaemic stroke. Age Ageing. 2020. [Epub ahead of print]. 31951248.

2020 Annals of Internal Medicine

55. In older patients in the ED, higher ERA scores were associated with increased risk for mortality and return visits. (Abstract)

In older patients in the ED, higher ERA scores were associated with increased risk for mortality and return visits. Espinoza Suarez NR, Walker LE, Jeffery MM, et al. Validation of the Elderly Risk Assessment index in the emergency department. Am J Emerg Med. 2019. [Epub ahead of print]. 31839521.

2020 Annals of Internal Medicine

56. Web Exclusive. Annals Consult Guys - Hydroxychloroquine: Update on an Old Drug. (Abstract)

Web Exclusive. Annals Consult Guys - Hydroxychloroquine: Update on an Old Drug. [Figure: see text].

2020 Annals of Internal Medicine

57. Efficacy of a tetravalent dengue vaccine in healthy children aged 4-16 years: a randomised, placebo-controlled, phase 3 trial. (Abstract)

Efficacy of a tetravalent dengue vaccine in healthy children aged 4-16 years: a randomised, placebo-controlled, phase 3 trial. A substantial unmet need remains for safe and effective vaccines against dengue virus disease, particularly for individuals who are dengue-naive and those younger than 9 years. We aimed to assess the efficacy, safety, and immunogenicity of a live attenuated tetravalent dengue vaccine (TAK-003) in healthy children aged 4-16 years.We present data up to 18 months post (...) -vaccination from an ongoing phase 3, randomised, double-blind trial of TAK-003 in endemic regions of Asia and Latin America (26 medical and research centres across Brazil, Colombia, Dominican Republic, Nicaragua, Panama, Philippines, Sri Lanka, and Thailand). Healthy children aged 4-16 years were randomly assigned 2:1 (stratified by age and region) to receive two doses of TAK-003 or two doses of placebo, 3 months apart. Investigators, participants and their parents or guardians, and sponsor

2020 Lancet

58. Safety and immunogenicity of a tetravalent dengue vaccine in children aged 2-17 years: a randomised, placebo-controlled, phase 2 trial. (Abstract)

Safety and immunogenicity of a tetravalent dengue vaccine in children aged 2-17 years: a randomised, placebo-controlled, phase 2 trial. An unmet clinical need remains for an effective tetravalent dengue vaccine suitable for all age groups, regardless of serostatus. We assessed the immunogenicity and safety of three different dose schedules of a tetravalent dengue vaccine (TAK-003) over a 48-month period in children living in dengue-endemic countries.We did a large, phase 2, double-blind (...) , placebo-controlled trial at three sites in the Dominican Republic, Panama, and the Philippines. Healthy participants aged 2-17 years were randomly assigned 1:2:5:1 using an interactive web response system with stratification by age to receive either a two-dose primary series (days 1 and 91), one primary dose (day 1), one primary dose plus booster (days 1 and 365), or placebo. Participants and relevant study personnel were masked to the random assignment until completion of the study at month 48

2020 Lancet

59. BSPED Interim Guideline for the Management of Children and Young People under the age of 18 years with Diabetic Ketoacidosis

BSPED Interim Guideline for the Management of Children and Young People under the age of 18 years with Diabetic Ketoacidosis BSPED Interim Guideline for the Management of Children and Young People under the age of 18 years with Diabetic Ketoacidosis The previous guideline for the management of DKA has been revised by the BSPED special interest group in diabetic ketoacidosis following a series of meetings. The relatively limited evidence regarding the management of DKA has been reviewed. Where (...) young people aged 16-18 years are managed by adult medical teams because of local arrangements, it is considered appropriate for them to be managed using local adult guidelines that the teams are familiar with rather than using potentially unfamiliar paediatric guidelines. Where individuals aged 16-18 are managed by Paediatric teams the Paediatric guidelines should be followed. 2) The ISPAD definition for DKA with acidosis and a bicarbonate of 3.0 mmol per litre has been adopted. The previous BSPED

2020 British Society for Paediatric Endocrinology and Diabetes

60. Interventions for anxiety in mainstream school-aged children with autism spectrum disorder (ASD) Full Text available with Trip Pro

the review as the impact of the intervention on only the ASD sample would be impossible to isolate. To be included in the review, either all participants in a study had to be of mainstream school age or a majority of participants had to be of mainstream school age. This meant that while most studies involved young people aged 6–16 years, one study (Piravej_2009) included some younger children (minimum 3 years old) and six studies included slightly older participants (MacKinnon_2014, Pryor_2016 (...) of anxiety for those with ASD varies widely (e.g., from 13% to 84%), the majority of studies suggest that a realistic estimate is between 40% and 50% (van Steensel, Bögels, & Perrin, ). The majority of studies undertaken exploring anxiety and ASD have focused on very young children, or older adolescents and adults. Fewer studies have been undertaken with school‐aged children, but those studies that have been conducted suggest a high co‐occurrence of anxiety in ASD populations of this age group (Ashburner

2020 Campbell Collaboration