Latest & greatest articles for pain

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Top results for pain

41. Injectable Botulinum Toxin for Pelvic Pain: A Review of Clinical Effectiveness, Cost-Effectiveness, and Guidelines

Injectable Botulinum Toxin for Pelvic Pain: A Review of Clinical Effectiveness, Cost-Effectiveness, and Guidelines Injectable Botulinum Toxin for Pelvic Pain: A Review of Clinical Effectiveness, Cost-Effectiveness, and Guidelines | CADTH.ca Find the information you need Injectable Botulinum Toxin for Pelvic Pain: A Review of Clinical Effectiveness, Cost-Effectiveness, and Guidelines Injectable Botulinum Toxin for Pelvic Pain: A Review of Clinical Effectiveness, Cost-Effectiveness (...) , and Guidelines Last updated: August 22, 2019 Project Number: RC1170-000 Product Line: Research Type: Drug Report Type: Summary with Critical Appraisal Result type: Report Question What is the clinical effectiveness of injectable botulinum toxin for pelvic floor pain? What is the cost-effectiveness of injectable botulinum toxin for pelvic floor pain? What are the evidence-based guidelines regarding injectable botulinum toxin for pelvic floor pain? Key Message Two systematic reviews and three randomized

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review

42. Medical Cannabis for the Treatment of Chronic Pain: A Review of Clinical Effectiveness and Guidelines

Medical Cannabis for the Treatment of Chronic Pain: A Review of Clinical Effectiveness and Guidelines Medical Cannabis for the Treatment of Chronic Pain: A Review of Clinical Effectiveness and Guidelines | CADTH.ca Find the information you need Medical Cannabis for the Treatment of Chronic Pain: A Review of Clinical Effectiveness and Guidelines Medical Cannabis for the Treatment of Chronic Pain: A Review of Clinical Effectiveness and Guidelines Last updated: July 24, 2019 Project Number: RC1153 (...) -000 Product Line: Research Type: Drug Report Type: Summary with Critical Appraisal Result type: Report Question What is the clinical effectiveness of medical cannabis for the treatment of chronic pain? What are the evidence-based guidelines associated with the use of medical cannabis for the treatment of chronic pain? Key Message Based on four overviews (with overlapping systematic reviews), and one systematic review of guidelines,8 there is some suggestion of benefit with cannabis-based medicines

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review

43. Wearables with Neuroreceptor Activation Patterns for Foot Neuropathy or Musculoskeletal Foot or Back Pain: Clinical Effectiveness

Wearables with Neuroreceptor Activation Patterns for Foot Neuropathy or Musculoskeletal Foot or Back Pain: Clinical Effectiveness Wearables with Neuroreceptor Activation Patterns for Foot Neuropathy or Musculoskeletal Foot or Back Pain: Clinical Effectiveness | CADTH.ca Find the information you need Wearables with Neuroreceptor Activation Patterns for Foot Neuropathy or Musculoskeletal Foot or Back Pain: Clinical Effectiveness Wearables with Neuroreceptor Activation Patterns for Foot Neuropathy (...) or Musculoskeletal Foot or Back Pain: Clinical Effectiveness Last updated: August 27, 2019 Project Number: RA1066-000 Product Line: Research Type: Devices and Systems Report Type: Reference List Result type: Report Question What is the clinical effectiveness of wearables incorporating a neuroreceptor activation sequence or pattern for foot neuropathy? What is the clinical effectiveness of wearables incorporating a neuroreceptor activation sequence or pattern for foot pain or back pain of musculoskeletal origin

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review

44. Cognitive Behavioural Therapy for Chronic Non-Cancer Pain: A Review of Clinical Effectiveness

Cognitive Behavioural Therapy for Chronic Non-Cancer Pain: A Review of Clinical Effectiveness Cognitive Behavioural Therapy for Chronic Non-Cancer Pain: A Review of Clinical Effectiveness | CADTH.ca Find the information you need Cognitive Behavioural Therapy for Chronic Non-Cancer Pain: A Review of Clinical Effectiveness Cognitive Behavioural Therapy for Chronic Non-Cancer Pain: A Review of Clinical Effectiveness Last updated: September 16, 2019 Project Number: RC1181-000 Product Line: Research (...) Type: Non-Pharma Mental Health Intervention Report Type: Summary with Critical Appraisal Result type: Report Question What is the clinical effectiveness of cognitive behavioural therapy for chronic non-cancer pain? Key Message There were five systematic reviews included in this report, four of which were Cochrane reviews. Four of the five included systematic reviews had one weakness in the AMSTAR critical domains. The clinical effectiveness of cognitive behavioural therapy was assessed in several

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review

45. Mindfulness Training and Yoga for the Management of Chronic Non-malignant Pain: A Review of Clinical Effectiveness and Cost-effectiveness

Mindfulness Training and Yoga for the Management of Chronic Non-malignant Pain: A Review of Clinical Effectiveness and Cost-effectiveness Mindfulness Training and Yoga for the Management of Chronic Non-malignant Pain: A Review of Clinical Effectiveness and Cost-effectiveness | CADTH.ca Find the information you need Mindfulness Training and Yoga for the Management of Chronic Non-malignant Pain: A Review of Clinical Effectiveness and Cost-effectiveness Mindfulness Training and Yoga (...) for the Management of Chronic Non-malignant Pain: A Review of Clinical Effectiveness and Cost-effectiveness Last updated: September 20, 2019 Project Number: RC1185-000 Product Line: Research Type: Devices and Systems Report Type: Summary with Critical Appraisal Result type: Report Question What is the clinical effectiveness of mindfulness training for chronic non-malignant pain in adults? What is the clinical effectiveness of yoga for chronic non-malignant pain in adults? What is the cost-effectiveness

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review

46. Manual Therapy for Persistent or Chronic Non-Specific Neck Pain: Clinical Effectiveness, Cost-Effectiveness and Guidelines

Manual Therapy for Persistent or Chronic Non-Specific Neck Pain: Clinical Effectiveness, Cost-Effectiveness and Guidelines Manual Therapy for Persistent or Chronic Non-Specific Neck Pain: Clinical Effectiveness, Cost-Effectiveness and Guidelines | CADTH.ca Find the information you need Manual Therapy for Persistent or Chronic Non-Specific Neck Pain: Clinical Effectiveness, Cost-Effectiveness and Guidelines Manual Therapy for Persistent or Chronic Non-Specific Neck Pain: Clinical Effectiveness (...) , Cost-Effectiveness and Guidelines Last updated: September 24, 2019 Project Number: RA1070-000 Product Line: Research Type: Devices and Systems Report Type: Reference List Result type: Report Question What is the clinical effectiveness of manual therapies for non-cancer, non-specific neck pain? What is the cost-effectiveness of manual therapies for non-cancer, non-specific neck pain? What are the evidence based guidelines regarding manual therapies for non-cancer, non-specific neck pain? Key Message

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review

47. Strength-based Exercise for Chronic Non-Cancer Back Pain: A Review of Clinical Effectiveness

Strength-based Exercise for Chronic Non-Cancer Back Pain: A Review of Clinical Effectiveness Strength-based Exercise for Chronic Non-Cancer Back Pain: A Review of Clinical Effectiveness | CADTH.ca Find the information you need Strength-based Exercise for Chronic Non-Cancer Back Pain: A Review of Clinical Effectiveness Strength-based Exercise for Chronic Non-Cancer Back Pain: A Review of Clinical Effectiveness Last updated: September 27, 2019 Project Number: RC1193-000 Product Line: Research (...) Type: Devices and Systems Report Type: Summary with Critical Appraisal Result type: Report Question What is the clinical effectiveness of strength-based exercise for chronic non-cancer back pain? Key Message No evidence was found regarding the clinical effectiveness of strength-based exercise alone compared with pharmacological interventions for chronic non-cancer back pain in non-pregnant people. Files Rapid Response Summary with Critical Appraisal Published : September 27, 2019 Follow us: © 2019

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review

48. Tiered Care for Chronic Non-Malignant Pain: A Review of Clinical Effectiveness, Cost-Effectiveness, and Guidelines

Tiered Care for Chronic Non-Malignant Pain: A Review of Clinical Effectiveness, Cost-Effectiveness, and Guidelines Tiered Care for Chronic Non-Malignant Pain: A Review of Clinical Effectiveness, Cost-Effectiveness, and Guidelines | CADTH.ca Find the information you need Tiered Care for Chronic Non-Malignant Pain: A Review of Clinical Effectiveness, Cost-Effectiveness, and Guidelines Tiered Care for Chronic Non-Malignant Pain: A Review of Clinical Effectiveness, Cost-Effectiveness (...) , and Guidelines Last updated: February 12, 2019 Project Number: RC1074-000 Product Line: Research Type: Devices and Systems Report Type: Summary with Critical Appraisal Result type: Report Question What is the clinical effectiveness of tiered or stepped care for patients with chronic, non-malignant pain in outpatient settings? What is the cost-effectiveness of tiered or stepped care for patients with chronic, non-malignant pain in outpatient settings? What are the evidence-based guidelines regarding tiered

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review

49. Extracorporeal shock wave therapy (ESWT) for heel pain

Extracorporeal shock wave therapy (ESWT) for heel pain 1 Translation of the key statement of the final report N15-06 Extrakorporale Stoßwellentherapie beim Fersenschmerz (Version 1.0; Status: 29 March 2017). Please note: This document was translated by an external translator and is provided as a service by IQWiG to English-language readers. However, solely the German original text is absolutely authoritative and legally binding. Extract IQWiG Reports – Commission No. N15-06 Extracorporeal shock (...) wave therapy (ESWT) for heel pain 1 Extract of final report N15-06 Version 1.0 ESWT for heel pain 29 March 2017 Institute for Quality and Efficiency in Health Care (IQWiG) - i - Publishing details Publisher: Institute for Quality and Efficiency in Health Care Topic: Extracorporeal shock wave therapy (ESWT) for heel pain Commissioning agency: Federal Joint Committee Commission awarded on: 30 July 2015 Internal Commission No.: N15-06 Address of publisher: Institut für Qualität und Wirtschaftlichkeit

2019 Institute for Quality and Efficiency in Healthcare (IQWiG)

50. Clinical Practice Guidelines and Consensus Statements About Pain Management in Critically Ill End-of-Life Patients: A Systematic Review

Clinical Practice Guidelines and Consensus Statements About Pain Management in Critically Ill End-of-Life Patients: A Systematic Review To identify and synthesize available recommendations from scientific societies and experts on pain management at the end-of-life in the ICU.We conducted a systematic review of PubMed, EMBASE, the Cochrane Database of Systematic Reviews, and Biblioteca Virtual en Salud from their inception until March 28, 2019.We included all clinical practice guidelines (...) , especially in the applicability and rigor of development. Most documents were in agreement on five topics: 1) using a quantitative tool for pain assessment; 2) administering narcotics for pain relief and benzodiazepines for anxiety relief; 3) against prescribing neuromuscular blockers during withdrawal of life support to assess pain; 4) endorsing the use of high doses of opioids and sedatives for pain control, regardless of the risk that they will hasten death; and 5) using quality indicators to improve

2019 EvidenceUpdates

51. The Efficacy, Tolerability, and Joint Safety of Fasinumab in Osteoarthritis Pain: A Phase IIb/III Double-Blind, Placebo-Controlled, Randomized Clinical Trial

The Efficacy, Tolerability, and Joint Safety of Fasinumab in Osteoarthritis Pain: A Phase IIb/III Double-Blind, Placebo-Controlled, Randomized Clinical Trial To prospectively assess the efficacy, general safety, and joint safety of fasinumab, an anti-nerve growth factor monoclonal antibody, in osteoarthritis (OA) hip and/or knee pain.Patients with moderate-to-severe OA pain (knee or hip) and history of inadequate response or intolerance to analgesics were randomized to receive fasinumab (at 1 (...) mg, 3 mg, 6 mg, or 9 mg) or placebo every 4 weeks over 16 weeks and were followed up to week 36. Efficacy end points were the change from baseline to week 16 in the pain and physical function subscale scores of the Western Ontario and McMaster Universities OA Index (WOMAC), and patient global assessment (PGA) of OA. Joints were monitored at scheduled assessments (by plain film radiography and magnetic resonance imaging) during treatment and follow-up, and if prompted, at the time of active joint

2019 EvidenceUpdates

52. Comparison of Oral Ibuprofen at Three Single-Dose Regimens for Treating Acute Pain in the Emergency Department: A Randomized Controlled Trial

Comparison of Oral Ibuprofen at Three Single-Dose Regimens for Treating Acute Pain in the Emergency Department: A Randomized Controlled Trial Nonsteroidal anti-inflammatory drugs (NSAIDs) are used extensively for the management of acute pain, with ibuprofen being one of the most frequently used oral analgesics in the emergency department (ED). We compare the analgesic efficacy of oral ibuprofen at 3 different doses for adult ED patients with acute pain.This was a randomized, double-blind trial (...) comparing analgesic efficacy of 3 doses of oral ibuprofen (400, 600, and 800 mg) in adult ED patients with acute painful conditions. Primary outcome included difference in pain scores between the 3 groups at 60 minutes.We enrolled 225 subjects (75 per group). The difference in mean pain scores at 60 minutes between the 400- and 600-mg groups was -0.14 (95% confidence interval [CI] -0.67 to 0.39); between the 400- and 800-mg groups, 0.14 (95% CI -0.65 to 0.37); and between the 600- and 800-mg groups

2019 EvidenceUpdates

53. Corticosteroid injection for plantar heel pain: a systematic review and meta-analysis

Corticosteroid injection for plantar heel pain: a systematic review and meta-analysis Corticosteroid injection is frequently used for plantar heel pain (plantar fasciitis), although there is limited high-quality evidence to support this treatment. Therefore, this study reviewed randomised trials to estimate the effectiveness of corticosteroid injection for plantar heel pain.A systematic review and meta-analysis of randomised trials that compared corticosteroid injection to any comparator (...) . Primary outcomes were pain and function, categorised as short (0 to 6 weeks), medium (7 to 12 weeks) or longer term (13 to 52 weeks).A total of 47 trials (2989 participants) were included. For reducing pain in the short term, corticosteroid injection was more effective than autologous blood injection (SMD -0.56; 95% CI, - 0.86 to - 0.26) and foot orthoses (SMD -0.91; 95% CI, - 1.69 to - 0.13). There were no significant findings in the medium term. In the longer term, corticosteroid injection was less

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2019 EvidenceUpdates

54. Timing of Pain Reassessment Post-Pharmacological Treatment Administration in Hospitals: Guidelines

Timing of Pain Reassessment Post-Pharmacological Treatment Administration in Hospitals: Guidelines Timing of Pain Reassessment Post-Pharmacological Treatment Administration in Hospitals: Guidelines | CADTH.ca Find the information you need Timing of Pain Reassessment Post-Pharmacological Treatment Administration in Hospitals: Guidelines Timing of Pain Reassessment Post-Pharmacological Treatment Administration in Hospitals: Guidelines Last updated: August 2, 2019 Project Number: RA1051-000 (...) Product Line: Research Type: Devices and Systems Report Type: Reference List Result type: Report Question What are the evidence-based guidelines regarding frequency and timing of pain reassessment following medication administration in hospital? Key Message Three evidence-based guidelines were identified regarding frequency and timing of pain reassessment following medication administration in hospital. Files Rapid Response Reference List Published : August 2, 2019 Related Content Follow us: © 2019

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review

55. No difference in pressure pain threshold and temporal summation after lumbar spinal manipulation compared to sham: A randomised controlled trial in adults with low back pain. (PubMed)

No difference in pressure pain threshold and temporal summation after lumbar spinal manipulation compared to sham: A randomised controlled trial in adults with low back pain. Changes in quantitative sensory tests have been observed after spinal manipulative therapy (SMT), particularly in pressure pain thresholds (PPT) and temporal summation (TS). However, a recent systematic review comparing SMT to sham found no significant difference in PPT in patients with musculoskeletal pain. The sham (...) -controlled studies were generally low quality, and conclusions about other quantitative sensory tests could not be made.We aimed to perform a sham-controlled study with the specific objective of investigating changes in PPT and TS short-term after lumbar SMT compared to sham manipulation in people with low back pain.This was a double-blind randomised controlled trial comparing high-velocity low-amplitude lumbar SMT against sham manipulation in participants with low back pain. Primary outcome measures

2019 Musculoskeletal science & practice Controlled trial quality: predicted high

56. Impact of different intraoperative CO2 pressure levels (8 and 15 mmHg) during laparoscopic hysterectomy performed due to benign uterine pathologies on postoperative pain and arterial pCO2 : a prospective randomised controlled clinical trial

Impact of different intraoperative CO2 pressure levels (8 and 15 mmHg) during laparoscopic hysterectomy performed due to benign uterine pathologies on postoperative pain and arterial pCO2 : a prospective randomised controlled clinical trial To compare the effects of two different intraoperative CO2 pressures (8 and 15 mmHg) during laparoscopic hysterectomy for benign uterine pathologies in terms of postoperative abdominal and shoulder pain, laparoscopy-mediated vegetative alterations, pain (...) medication requirement, arterial CO2 pressure (pCO2 ), surgical parameters, and safety.Prospective randomised controlled study.German university hospital.Female patients undergoing laparoscopic hysterectomy for benign uterine pathologies.Patients were randomised to a standard pressure (SP; 15 mmHg, control) or low-pressure (LP; 8 mmHg, experimental) group.Primary outcomes were postoperative abdominal and shoulder pain intensities, measured via numeric rating scale (NRS) and vegetative parameters (fatigue

2019 EvidenceUpdates

57. Are beta blockers safe to use in cocaine-related chest pain?

Are beta blockers safe to use in cocaine-related chest pain? Chiefs’ Inquiry Corner – 8/26/19 – Clinical Correlations Search Chiefs’ Inquiry Corner – 8/26/19 August 26, 2019 2 min read The classic teaching that beta blockers should be avoided in patients who actively use cocaine is a subject of debate. There is the theoretical risk of “unopposed alpha effect” which is based on very small human studies, case reports, and some small animal studies. For example, there are only two prospective

2019 Clinical Correlations

58. Statement on Environmental Sustainability in Anaesthesia and Pain Medicine Practice

Statement on Environmental Sustainability in Anaesthesia and Pain Medicine Practice PS64 2019 Page 1 PS64 2019 Australian and New Zealand College of Anaesthetists (ANZCA) Faculty of Pain Medicine Statement on Environmental Sustainability in Anaesthesia and Pain Medicine Practice 1. PURPOSE The purpose of this statement is: 1.1 to affirm ANZCA’s commitment to minimising the health impact of climate change and promoting environmental sustainability. 1.2 to serve as a resource for clinicians (...) to promote environmentally sustainable practices in their workplace. 1.3 to assist healthcare facilities in embedding sustainable practices in the delivery of safe patient care. 2. SCOPE This document is intended to apply to all clinicians practising anaesthesia, perioperative medicine and pain medicine, and all healthcare facilities in which anaesthesia, perioperative and pain medicine services are provided. 3. BACKGROUND The healthcare sector is highly interconnected with activities that emit pollution

2019 Australian and New Zealand College of Anaesthetists

59. Comparative Effectiveness of Analgesics To Reduce Acute Pain in the Prehospital Setting

Comparative Effectiveness of Analgesics To Reduce Acute Pain in the Prehospital Setting Comparative Effectiveness of Analgesics To Reduce Acute Pain in the Prehospital Setting Comparative Effectiveness Review Number 220 R Comparative Effectiveness Review Number 220 Comparative Effectiveness of Analgesics To Reduce Acute Pain in the Prehospital Setting Prepared for: Agency for Healthcare Research and Quality U.S. Department of Health and Human Services 5600 Fishers Lane Rockville, MD 20857 (...) analgesics as treatment of moderate to severe acute pain in the prehospital setting. Key Messages • As initial therapy in the prehospital setting: o Nonsteroidal anti-inflammatory drugs provide similar pain relief to opioids and may cause fewer overall side effects and less drowsiness. o Acetaminophen may provide similar pain relief to opioids, and may cause fewer side effects overall and less dizziness. o Ketamine may provide similar pain relief to opioids. Ketamine may cause more dizziness or overall

2019 Effective Health Care Program (AHRQ)

60. Oral morphine analgesia for preventing pain during invasive procedures in non-ventilated premature infants in hospital: the Poppi RCT

Oral morphine analgesia for preventing pain during invasive procedures in non-ventilated premature infants in hospital: the Poppi RCT Oral morphine analgesia for preventing pain during invasive procedures in non-ventilated premature infants in hospital: the Poppi RCT Journals Library An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found. Please choose a page from the navigation or try (...) a website search above to find the information you need. >> >> >> >> Issue {{metadata .Issue }} Toolkit 1)"> 0)"> 1)"> {{metadata.Title}} {{metadata.Headline}} The trial was stopped early because of profound respiratory adverse effects, without evidence of analgesic benefit for procedural pain, from the administration of oral morphine to non-ventilated premature infants. {{author}} {{($index , , , , , , , , , , , & . Vaneesha Monk 1, *, † , Fiona Moultrie 1, † , Caroline Hartley 1 , Amy Hoskin 1

2019 NIHR HTA programme