Latest & greatest articles for pain

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Top results for pain

4161. Analgesic efficacy of ibuprofen alone and in combination with codeine or caffeine in post-surgical pain: a meta-analysis

Analgesic efficacy of ibuprofen alone and in combination with codeine or caffeine in post-surgical pain: a meta-analysis Analgesic efficacy of ibuprofen alone and in combination with codeine or caffeine in post-surgical pain: a meta-analysis Analgesic efficacy of ibuprofen alone and in combination with codeine or caffeine in post-surgical pain: a meta-analysis Li Wan Po A, Zhang W Y Authors' objectives To estimate the analgesic effect of ibuprofen, and to test whether codeine and caffeine (...) enhance its effect on postsurgical pain. Searching MEDLINE, Excerpta Medica and the ISI database (from 1966 to December 1996) were searched using MeSH and keywords (not given). The reference lists of retrieved reports and review articles were also checked. Only English language articles were considered. Study selection Study designs of evaluations included in the review Randomised controlled trials (RCTs) of placebo and headtohead evaluations. Double-blind, single-blind, crossover and parallel studies

1998 DARE.

4162. A systematic review of lidocaine-prilocaine cream (EMLA) in the treatment of acute pain in neonates

A systematic review of lidocaine-prilocaine cream (EMLA) in the treatment of acute pain in neonates A systematic review of lidocaine-prilocaine cream (EMLA) in the treatment of acute pain in neonates A systematic review of lidocaine-prilocaine cream (EMLA) in the treatment of acute pain in neonates Taddio A, Ohlsson A, Einarson T R, Stevens B, Koren G Authors' objectives To determine the efficacy and safety of lidocaine-prilocaine 5% cream (EMLA) as an analgesic for procedural pain treatment (...) in neonates and provide evidence-based recommendations for clinical practice. Searching The following electronic databases were searched: MEDLINE (Jan 1966-Dec 1996), EMBASE (1993-1996) and Reference Update (Jan 1995-Dec 1996); using the MeSH terms/textwords: 'infant-newborn', 'pain', 'analgesic', 'anesthesia', 'EMLA', 'lidocaine-prilocaine', and 'local anesthetics'. In addition manual searches of bibliographies, personal files, scientific meeting proceedings, and recent issues of key journals were

1998 DARE.

4163. Comparing analgesic efficacy of non-steroidal anti-inflammatory drugs given by different routes in acute and chronic pain: a qualitative systematic review

Comparing analgesic efficacy of non-steroidal anti-inflammatory drugs given by different routes in acute and chronic pain: a qualitative systematic review Comparing analgesic efficacy of non-steroidal anti-inflammatory drugs given by different routes in acute and chronic pain: a qualitative systematic review Comparing analgesic efficacy of non-steroidal anti-inflammatory drugs given by different routes in acute and chronic pain: a qualitative systematic review Tramer M R, Williams J E, Carroll (...) D, Wiffen P J, Moore R A, McQuay H J Authors' objectives To assess the evidence for a difference in analgesic efficacy and adverse effects of non-steroidal anti-inflammatory drugs (NSAIDs) given by different routes. Searching MEDLINE from 1966 to 1996, EMBASE from 1986 to 1996, and the Oxford Pain Relief Database from 1950 to 1993, were searched using the keywords 'NSAID' and 'non-steroidal anti-inflammatory'. Searches were also conducted with the individual drug names in combination with 'post

1998 DARE.

4164. Do antidepressants have an analgesic effect in psychogenic pain and somatoform pain disorder: a meta-analysis

Do antidepressants have an analgesic effect in psychogenic pain and somatoform pain disorder: a meta-analysis Do antidepressants have an analgesic effect in psychogenic pain and somatoform pain disorder: a meta-analysis Do antidepressants have an analgesic effect in psychogenic pain and somatoform pain disorder: a meta-analysis Fishbain D A, Cutler R B, Rosomoff H L, Rosomoff R S. Authors' objectives To determine whether antidepressants have an analgesic effect in psychogenic pain (...) and somatoform pain disorder. Searching The following electronic databases were searched: MEDLINE (1966-), PsycINFO (1966-), Science Citation Index (1974-) and the National Library of Medicine Database (1966-). The following MeSH terms were used as search terms: 'pain and antidepressants', 'psychogenic pain or somatoform pain disorder' and 'antidepressants'. Manual searches of pain treatment outcome literature, pain books and pain meetings abstracts were also carried out. English and non-English language

1998 DARE.

4165. Clinical value of acute rest technetium-99m tetrofosmin tomographic myocardial perfusion imaging in patients with acute chest pain and non-diagnostic electrocardiograms

Clinical value of acute rest technetium-99m tetrofosmin tomographic myocardial perfusion imaging in patients with acute chest pain and non-diagnostic electrocardiograms Clinical value of acute rest technetium-99m tetrofosmin tomographic myocardial perfusion imaging in patients with acute chest pain and non-diagnostic electrocardiograms Clinical value of acute rest technetium-99m tetrofosmin tomographic myocardial perfusion imaging in patients with acute chest pain and non-diagnostic (...) -photon emission computed tomographic (SPECT) myocardial perfusion imaging in patients with a suspected myocardial infarction (MI) but a normal or non-diagnostic electrocardiogram (ECG). Patients were given an injection of 20 to 30 MCI of Tc-99 tetrofosmin at rest and SPECT imaging data were acquired between 15 minutes and 3 hours afterwards. Type of intervention Diagnosis. Economic study type Cost-effectiveness analysis. Study population Patients presenting to emergency departments with chest pain

1998 NHS Economic Evaluation Database.

4166. Brief courses of palliative radiotherapy for metastatic bone pain: a pilot cost-minimization comparison with narcotic analgesics

Brief courses of palliative radiotherapy for metastatic bone pain: a pilot cost-minimization comparison with narcotic analgesics Brief courses of palliative radiotherapy for metastatic bone pain: a pilot cost-minimization comparison with narcotic analgesics Brief courses of palliative radiotherapy for metastatic bone pain: a pilot cost-minimization comparison with narcotic analgesics Macklis R M, Cornelli H, Lasher J Record Status This is a critical abstract of an economic evaluation that meets (...) the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The use of palliative radiotherapy for metastatic bone pain. The study did not include a clearly defined comparator. The outcomes were measured before and after the treatment. The costs were compared with the published costs for narcotic pain regimens. Type

1998 NHS Economic Evaluation Database.

4167. Health economic assessment of behavioural rehabilitation in chronic low back pain: a randomised clinical trial

Health economic assessment of behavioural rehabilitation in chronic low back pain: a randomised clinical trial Health economic assessment of behavioural rehabilitation in chronic low back pain: a randomised clinical trial Health economic assessment of behavioural rehabilitation in chronic low back pain: a randomised clinical trial Goossens M E, Rutten-van Molken M P, Kole-Snijders A M, Vlaeyen J W, Van Breukelen G, Leidl R Record Status This is a critical abstract of an economic evaluation (...) that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Behavioural rehabilitation programmes of chronic low back pain: OPCON (operant programme with cognitive programme/relaxation), OPDIM (operant programme with a group discussion treatment) and USUAL (operant rehabilitation as usual). Type of intervention

1998 NHS Economic Evaluation Database.

4168. One-year follow-up comparison of the cost and effectiveness of chiropractic and physiotherapy as primary management for back pain: subgroup analysis, recurrence, and additional health care utilization

One-year follow-up comparison of the cost and effectiveness of chiropractic and physiotherapy as primary management for back pain: subgroup analysis, recurrence, and additional health care utilization One-year follow-up comparison of the cost and effectiveness of chiropractic and physiotherapy as primary management for back pain: subgroup analysis, recurrence, and additional health care utilization One-year follow-up comparison of the cost and effectiveness of chiropractic and physiotherapy (...) as primary management for back pain: subgroup analysis, recurrence, and additional health care utilization Skargren E I, Carlsson P G, Oberg B E Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Primary management of back and neck pain

1998 NHS Economic Evaluation Database.

4169. The clinical and economic value of a short course of omeprazole in patients with noncardiac chest pain

The clinical and economic value of a short course of omeprazole in patients with noncardiac chest pain The clinical and economic value of a short course of omeprazole in patients with noncardiac chest pain The clinical and economic value of a short course of omeprazole in patients with noncardiac chest pain Fass R, Fennerty M B, Ofman J J, Gralnek I M, Johnson C, Camargo E, Sampliner R E Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion (...) on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The use of the omeprazole test, compared with placebo, as a diagnostic test for detecting gastroesophageal reflux disease (GERD) in patients with noncardiac chest pain (NCCP). The omeprazole test consisted of a short course of high-dose omeprazole. Type of intervention Diagnosis. Economic

1998 NHS Economic Evaluation Database.

4170. A comparison of physical therapy, chiropractic manipulation, and provision of an educational booklet for the treatment of patients with lower back pain

A comparison of physical therapy, chiropractic manipulation, and provision of an educational booklet for the treatment of patients with lower back pain Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

1998 NHS Economic Evaluation Database.

4171. Lumbar supports and education for the prevention of low back pain in industry: a randomized controlled trial. (PubMed)

Lumbar supports and education for the prevention of low back pain in industry: a randomized controlled trial. Low back pain is a frequent and costly health problem. Prevention of low back pain is important both for the individual patient and from an economic perspective.To assess the efficacy of lumbar supports and education in the prevention of low back pain in industry.A randomized controlled trial with a factorial design.The cargo department of an airline company in the Netherlands.A total (...) of 312 workers were randomized, of whom 282 were available for the 6-month follow-up.Subjects were randomly assigned to 4 groups: (1) education (lifting instructions) and lumbar support, (2) education, (3) lumbar support, and (4) no intervention. Education consisted of 3 group sessions on lifting techniques with a total duration of 5 hours. Lumbar supports were recommended to be used during working hours for 6 months.Low back pain incidence and sick leave because of back pain during the 6-month

1998 JAMA Controlled trial quality: predicted high

4172. A comparison of physical therapy, chiropractic manipulation, and provision of an educational booklet for the treatment of patients with low back pain. (PubMed)

A comparison of physical therapy, chiropractic manipulation, and provision of an educational booklet for the treatment of patients with low back pain. There are few data on the relative effectiveness and costs of treatments for low back pain. We randomly assigned 321 adults with low back pain that persisted for seven days after a primary care visit to the McKenzie method of physical therapy, chiropractic manipulation, or a minimal intervention (provision of an educational booklet). Patients (...) between the physical-therapy and chiropractic groups and no significant differences among the groups in the numbers of days of reduced activity or missed work or in recurrences of back pain. About 75 percent of the subjects in the therapy groups rated their care as very good or excellent, as compared with about 30 percent of the subjects in the booklet group (P<0.001). Over a two-year period, the mean costs of care were $437 for the physical-therapy group, $429 for the chiropractic group, and $153

Full Text available with Trip Pro

1998 NEJM Controlled trial quality: uncertain

4173. Effectiveness of corticosteroid injections versus physiotherapy for treatment of painful stiff shoulder in primary care: randomised trial. (PubMed)

Effectiveness of corticosteroid injections versus physiotherapy for treatment of painful stiff shoulder in primary care: randomised trial. To compare the effectiveness of corticosteroid injections with physiotherapy for the treatment of painful stiff shoulder.Randomised trial.40 general practices.109 patients consulting general practitioners for shoulder pain were enrolled in the trial.Patients were randomly allocated to 6 weeks of treatment either with corticosteroid injections (53 (...) ) or physiotherapy (56).Outcome assessments were carried out 3, 7, 13, 26, and 52 weeks after randomisation; some of the assessments were done by an observer blind to treatment allocation. Primary outcome measures were the success of treatment as measured by scores on scales measuring improvement in the main complaint and pain, and improvement in scores on a scale measuring shoulder disability.At 7 weeks 40 (77%) out of 52 patients treated with injections were considered to be treatment successes compared

Full Text available with Trip Pro

1998 BMJ Controlled trial quality: predicted high

4174. Double-blind randomised controlled trial of effect of metronidazole on pain after day-case haemorrhoidectomy. (PubMed)

Double-blind randomised controlled trial of effect of metronidazole on pain after day-case haemorrhoidectomy. Haemorrhoidectomy is commonly an inpatient procedure because patients and doctors worry about postoperative pain. Day-case haemorrhoidectomy (DCH) is possible if patient anxiety is addressed and postoperative pain and bowel function are managed. Pain sometimes increases a few days after haemorrhoidectomy, possibly because of secondary infection. We studied the effect of metronidazole (...) on pain after DCH.We randomly assigned 40 consecutive patients admitted for DCH metronidazole 400 mg (n = 20) or placebo (n = 20) three times daily, both for 7 days. All patients received lactulose from 2 days before surgery for 2 weeks. Diathermy DCH was performed without pedicle ligature or anal-canal dressing, and a diclofenac suppository was administered at the end of the procedure. Patients were discharged on the same day with diclofenac, 0.2% glyceryl-trinitrate ointment, lactulose, a telephone

1998 Lancet Controlled trial quality: predicted high

4175. Acupuncture and amitriptyline for pain due to HIV-related peripheral neuropathy: a randomized controlled trial. Terry Beirn Community Programs for Clinical Research on AIDS. (PubMed)

Acupuncture and amitriptyline for pain due to HIV-related peripheral neuropathy: a randomized controlled trial. Terry Beirn Community Programs for Clinical Research on AIDS. Peripheral neuropathy is common in persons infected with the human immunodeficiency virus (HIV) but few data on symptomatic treatment are available.To evaluate the efficacy of a standardized acupuncture regimen (SAR) and amitriptyline hydrochloride for the relief of pain due to HIV-related peripheral neuropathy in HIV (...) -associated, symptomatic, lower-extremity peripheral neuropathy. Of 250 patients enrolled, 239 were in the acupuncture comparison (125 in the factorial option and 114 in the SAR option vs control points option), and 136 patients were in the amitriptyline comparison (125 in the factorial option and 11 in amitriptyline option vs placebo option).Standardized acupuncture regimen vs control points, amitriptyline (75 mg/d) vs placebo, or both for 14 weeks.Changes in mean pain scores at 6 and 14 weeks, using

1998 JAMA Controlled trial quality: predicted high

4176. Gabapentin for the symptomatic treatment of painful neuropathy in patients with diabetes mellitus: a randomized controlled trial. (PubMed)

Gabapentin for the symptomatic treatment of painful neuropathy in patients with diabetes mellitus: a randomized controlled trial. Pain is the most disturbing symptom of diabetic peripheral neuropathy. As many as 45% of patients with diabetes mellitus develop peripheral neuropathies.To evaluate the effect of gabapentin monotherapy on pain associated with diabetic peripheral neuropathy.Randomized, double-blind, placebo-controlled, 8-week trial conducted between July 1996 and March 1997.Outpatient (...) clinics at 20 sites.The 165 patients enrolled had a 1- to 5-year history of pain attributed to diabetic neuropathy and a minimum 40-mm pain score on the Short-Form McGill Pain Questionnaire visual analogue scale.Gabapentin (titrated from 900 to 3600 mg/d or maximum tolerated dosage) or placebo.The primary efficacy measure was daily pain severity as measured on an 11-point Likert scale (0, no pain; 10, worst possible pain). Secondary measures included sleep interference scores, the Short-Form McGill

1998 JAMA Controlled trial quality: predicted high

4177. A clinical trial of a chest-pain observation unit for patients with unstable angina. Chest Pain Evaluation in the Emergency Room (CHEER) Investigators. (PubMed)

A clinical trial of a chest-pain observation unit for patients with unstable angina. Chest Pain Evaluation in the Emergency Room (CHEER) Investigators. Nearly half of patients hospitalized with unstable angina eventually receive a non-cardiac-related diagnosis, yet 5 percent of patients with myocardial infarction are inappropriately discharged from the emergency department. We evaluated the safety, efficacy, and cost of admission to a chest-pain observation unit (CPU) located in the emergency

1998 NEJM Controlled trial quality: uncertain

4178. Electrical spinal-cord stimulation for painful diabetic peripheral neuropathy. (PubMed)

Electrical spinal-cord stimulation for painful diabetic peripheral neuropathy. Conventional treatment for painful peripheral diabetic neuropathy is largely symptomatic and often ineffective, with unacceptable side-effects. We tested electrical spinal-cord stimulation for the management of chronic neuropathic pain.Ten diabetic patients who did not respond to conventional treatment (mean age 51 [SD 9.3] years, six with type II diabetes, mean duration of diabetes 12 [6.3] years, mean duration (...) of neuropathy 5 [2.1] years) were studied. The electrode was implanted in the thoracic/lumbar epidural space. Immediate neuropathic pain relief was assessed by visual analogue scale (VAS) after connecting the electrode, in a random order, to a percutaneous electrical stimulator or to a placebo stimulator. Exercise tolerance was assessed on a treadmill.Eight subjects had statistically significant pain relief with the electrical stimulator (p < 0.02) and were therefore converted to a permanent system

1997 Lancet Controlled trial quality: uncertain

4179. In-patient vs out-patient pain management programmes that adopt a cognitive behavioural approach

In-patient vs out-patient pain management programmes that adopt a cognitive behavioural approach In-patient vs out-patient pain management programmes that adopt a cognitive behavioural approach In-patient vs out-patient pain management programmes that adopt a cognitive behavioural approach Evans R Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database (...) . Citation Evans R. In-patient vs out-patient pain management programmes that adopt a cognitive behavioural approach. Southampton: Wessex Institute for Health Research and Development (WIHRD) 1997 Authors' objectives The author aims to determine whether in-patient pain management centres that adopt a behavioural approach confer any benefit over out-patient therapy that adopt similar practices. Authors' conclusions The author concludes that the evidence of effectiveness and cost-utility ratio described

1997 Health Technology Assessment (HTA) Database.

4180. Systematic review of outpatient services for chronic pain control

Systematic review of outpatient services for chronic pain control Systematic review of outpatient services for chronic pain control Systematic review of outpatient services for chronic pain control McQuay HJ, Moore RA, Eccleston C, Morley S, de C Williams AC Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation McQuay HJ, Moore RA, Eccleston C (...) , Morley S, de C Williams AC. Systematic review of outpatient services for chronic pain control. Health Technology Assessment 1997; 1(6): 1-137 Authors' objectives This report reviews the evidence about the effectiveness of treatments for chronic pain. While treatment of chronic pain is usually seen as an integrated service, this report concentrates on the individual interventions that constitute the service. Authors' conclusions The findings show that there is excellent evidence of effectiveness

1997 Health Technology Assessment (HTA) Database.