Latest & greatest articles for menopause

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on menopause or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on menopause and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

What is Trip?

Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.

Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.

As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.

For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via jon.brassey@tripdatabase.com

Top results for menopause

1. Are vaginal estradiol tablets (Vagifem) effective for genitourinary syndrome of menopause?

Are vaginal estradiol tablets (Vagifem) effective for genitourinary syndrome of menopause? Tools for Practice is proudly sponsored by the Alberta College of Family Physicians (ACFP). ACFP is a provincial, professional voluntary organization, representing more than 4,800 family physicians, family medicine residents, and medical students in Alberta. Established over sixty years ago, the ACFP strives for excellence in family practice through advocacy, continuing medical education and primary care (...) research. www.acfp.ca June 10, 2019 Verifying the value of vaginal estradiol tablets Clinical Question: Are vaginal estradiol tablets (Vagifem®) effective for genitourinary syndrome of menopause? Bottom Line: Vaginal estradiol tablets are likely no better than placebo vaginal gel for reducing “most bothersome symptom scores” (mainly dyspareunia). However, compared to placebo vaginal tablets, they reduce symptoms (example: treatment “success” at 12 months in 86% versus 41% placebo). A non-medicated

2019 Tools for Practice

2. Menopause

Menopause Menopause - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Menopause Last reviewed: February 2019 Last updated: February 2019 Summary The diagnosis is clinical, based on the absence of menses for 12 months, and does not require further testing for appropriately presenting patients. Oestrogen therapy is an effective treatment for the management of menopausal symptoms including hot flushes, night sweats (...) , and is unlikely to increase the risk of stroke or venous thrombosis above that of non-users. Non-hormonal interventions may help women who have a contraindication to, or cannot tolerate, HT. However, they are less effective than HT in controlling menopausal symptoms. Definition Onset of the menopause is heralded by the cessation of menses for at least 12 consecutive months, without some other reason for amenorrhoea (such as pregnancy, hormone therapy, or other medical condition). No further testing

2019 BMJ Best Practice

3. Treatments for reducing menopausal hot flushes are ranked for effectiveness

Treatments for reducing menopausal hot flushes are ranked for effectiveness Treatments for reducing menopausal hot flushes are ranked for effectiveness Discover Portal Discover Portal Treatments for reducing menopausal hot flushes are ranked for effectiveness Published on 25 July 2017 doi: A combination of oestrogen and progestogen via patches is the best treatment for menopause symptoms. Other options may be less beneficial, including tablets combining oestrogen and progestogen, and non (...) -hormonal treatments, isoflavones and black cohosh, though they may have other benefits. There is no evidence to support the use of antidepressants. Menopause affects women’s personal life and work life, but many don’t seek help from healthcare professionals. It is important to identify the most effective and safest treatment to help women in this transitional period. This review compared treatment options for the short-term management of hot flushes and night sweats in women aged 45 years or older who

2019 NIHR Dissemination Centre

4. Effects of acute dietary nitrate supplementation on aortic blood pressures and pulse wave characteristics in post-menopausal women. (PubMed)

Effects of acute dietary nitrate supplementation on aortic blood pressures and pulse wave characteristics in post-menopausal women. Consumption of nitrate-rich beetroot juice can lower blood pressure in peripheral as well as central arteries and may exert additional hemodynamic benefits (e.g. reduced aortic wave reflections). The specific influence of nitrate supplementation on arterial pressures and aortic wave properties in postmenopausal women, a group that experiences accelerated increases (...) ± 1 yr) before and 100 min after consumption of 140 ml of either nitrate-rich (9.7 mmol, 0.6 gm NO3-) or nitrate-depleted beetroot juice on randomized visits approximately 10 days apart (cross-over design). Ten young premenopausal women (22 ± 1 yr) served as a reference (non-supplemented) cohort.Brachial and derived-aortic variables showed the expected age-associated differences in these women (all p < 0.05). In post-menopausal women, nitrate supplementation reduced (p < 0.05 vs. placebo visit

2019 Nitric oxide : biology and chemistry

5. A systematic review assessing the efficacy of treatments for genitourinary symptoms of menopause in women with breast cancer

A systematic review assessing the efficacy of treatments for genitourinary symptoms of menopause in women with breast cancer Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any

2019 PROSPERO

6. The efficacy and safety of isoflavone treatment in post-menopausal women with osteoporosis: a systematic review and meta-analysis

The efficacy and safety of isoflavone treatment in post-menopausal women with osteoporosis: a systematic review and meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record

2019 PROSPERO

7. The potential of Labisia pumila for the treatment of post-menopausal osteoporosis

The potential of Labisia pumila for the treatment of post-menopausal osteoporosis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email

2019 PROSPERO

8. The effect of oxytocin on vaginal atrophy in menopausal women

The effect of oxytocin on vaginal atrophy in menopausal women Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr

2019 PROSPERO

9. Early menopause and physical performance in women: a systematic review

Early menopause and physical performance in women: a systematic review Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation

2019 PROSPERO

10. Feasibility of different treatments for sleep disturbance in peri-menopause and post-menopause breast cancer patients: a systematic review

Feasibility of different treatments for sleep disturbance in peri-menopause and post-menopause breast cancer patients: a systematic review Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration

2019 PROSPERO

11. Fracture risk reduction by anti-osteoporosis pharmacotherapy according to baseline fracture risk among post-menopausal women (protocol for a systematic review and meta-analysis of randomised trials)

Fracture risk reduction by anti-osteoporosis pharmacotherapy according to baseline fracture risk among post-menopausal women (protocol for a systematic review and meta-analysis of randomised trials) Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears

2019 PROSPERO

12. Efficacy of combination therapy of anabolic agents and bisphophonates compared to bisphosphonates alone on bone mineral density and fracture risk in post menopausal osteoporosis: a meta-analysis of randomized controlled trials

Efficacy of combination therapy of anabolic agents and bisphophonates compared to bisphosphonates alone on bone mineral density and fracture risk in post menopausal osteoporosis: a meta-analysis of randomized controlled trials Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate

2019 PROSPERO

13. Quality assessment of interventional studies on energy based treatments for the management of the genitourinary symptoms of menopause and stress urinary incontinence: a systematic review

Quality assessment of interventional studies on energy based treatments for the management of the genitourinary symptoms of menopause and stress urinary incontinence: a systematic review Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility

2019 PROSPERO

14. Mindfulness-based stress reduction for menopausal symptoms after risk-reducing salpingo-oophorectomy (PURSUE study): a randomised controlled trial

Mindfulness-based stress reduction for menopausal symptoms after risk-reducing salpingo-oophorectomy (PURSUE study): a randomised controlled trial To assess the short- and long-term effects of mindfulness-based stress reduction (MBSR) on the resulting quality of life, sexual functioning, and sexual distress after risk-reducing salpingo-oophorectomy (RRSO).Randomised controlled trial.A specialised family cancer clinic of the university medical center Groningen.Sixty-six women carriers (...) of the BRCA1/2 mutation who developed at least two moderate-to-severe menopausal symptoms after RRSO.Women were randomised to an 8-week MBSR training programme or to care as usual (CAU).Change in the Menopause-Specific Quality of Life Questionnaire (MENQOL), the Female Sexual Function Index, and the Female Sexual Distress Scale, administered from baseline at 3, 6, and 12 months. Linear mixed modelling was applied to compare the effect of MBSR with CAU over time.At 3 and 12 months, there were statistically

2018 EvidenceUpdates

15. Acupuncture for symptoms in menopause transition: a randomized controlled trial

Acupuncture for symptoms in menopause transition: a randomized controlled trial Acupuncture has been used for women during menopause transition, but evidence is limited.We sought to evaluate the efficacy of electroacupuncture on relieving symptoms of women during menopause transition.We conducted a prospective, multicenter, randomized, participant-blinded trial in China mainland. Subjects were randomized to receive 24 treatment sessions of electroacupuncture at traditional acupoints or sham (...) electroacupuncture at nonacupoints over 8 weeks with 24 weeks' follow-up. Primary outcome was the change from baseline in the total score of Menopause Rating Scale at week 8. Secondary outcomes included the changes from baseline in the average 24-hour hot flash score, the Menopause Rating Scale subscale scores, the total score of Menopause-Specific Quality of Life Questionnaire and its subscales, and serum female hormones. All analyses were performed with a 2-sided P value of < .05 considered significant based

2018 EvidenceUpdates

16. Menopause

Menopause Top results for menopause - Trip Database or use your Google+ account Turning Research Into Practice ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing the search button. An example search might look like (#1 or #2) and (#3 (...) or #4) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for menopause The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence

2018 Trip Latest and Greatest

17. Menopause

Menopause Evidence Maps - Trip Database or use your Google+ account Turning Research Into Practice ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing the search button. An example search might look like (#1 or #2) and (#3 or #4

2018 Trip Evidence Maps

18. Mindfulness, cognitive behavioural and behaviour-based therapy for natural and treatment-induced menopausal symptoms: a systematic review and meta-analysis

Mindfulness, cognitive behavioural and behaviour-based therapy for natural and treatment-induced menopausal symptoms: a systematic review and meta-analysis During menopause women experience vasomotor and psychosexual symptoms that cannot entirely be alleviated with hormone replacement therapy (HRT). Besides, HRT is contraindicated after breast cancer.To review the evidence on the effectiveness of psychological interventions in reducing symptoms associated with menopause in natural or treatment (...) -induced menopausal women.Medline/Pubmed, PsycINFO, EMBASE and AMED were searched until June 2017.Randomised controlled trials (RCTs) concerning natural or treatment-induced menopause, investigating mindfulness or (cognitive-)behaviour-based therapy were selected. Main outcomes were frequency of hot flushes, hot flush bother experienced, other menopausal symptoms and sexual functioning.Study selection and data extraction were performed by two independent researchers. A meta-analysis was performed

Full Text available with Trip Pro

2018 EvidenceUpdates

19. Treatments for reducing menopausal hot flushes are ranked for effectiveness

Treatments for reducing menopausal hot flushes are ranked for effectiveness Treatments for reducing menopausal hot flushes are ranked for effectiveness Discover Portal Discover Portal Treatments for reducing menopausal hot flushes are ranked for effectiveness Published on 25 July 2017 doi: A combination of oestrogen and progestogen via patches is the best treatment for menopause symptoms. Other options may be less beneficial, including tablets combining oestrogen and progestogen, and non (...) -hormonal treatments, isoflavones and black cohosh, though they may have other benefits. There is no evidence to support the use of antidepressants. Menopause affects women’s personal life and work life, but many don’t seek help from healthcare professionals. It is important to identify the most effective and safest treatment to help women in this transitional period. This review compared treatment options for the short-term management of hot flushes and night sweats in women aged 45 years or older who

2018 NIHR Dissemination Centre

20. Longitudinal Effects of Adjuvant Endocrine Therapy on the Quality of Life of Post-menopausal Women with Non-metastatic ER+ Breast Cancer: A Systematic Review.

Longitudinal Effects of Adjuvant Endocrine Therapy on the Quality of Life of Post-menopausal Women with Non-metastatic ER+ Breast Cancer: A Systematic Review. Anti-estrogen (ER) endocrine therapy is an effective treatment strategy in reducing breast cancer mortality. This therapy has a better therapeutic index than chemotherapy but can still affect patients' quality of life (QOL) over time.The objectives of this systematic review were to (1) describe QOL instruments used in ER-positive (ER (...) +) non-metastatic breast cancer trials and (2) document the longitudinal effects of adjuvant endocrine therapy on the QOL of post-menopausal women with ER+ non-metastatic breast cancer.We searched three electronic bibliographic databases for articles published from inception to October 2017 that described (1) a randomized controlled trial (RCT) of non-metastatic breast cancer containing an adjuvant endocrine regimen in at least one arm; (2) the use of a patient self-report measure assessing general

Full Text available with Trip Pro

2018 PharmacoEconomics - open